Elsevier

Injury

Volume 40, Issue 4, April 2009, Pages 354-357
Injury

Does age matter? The relationship between age and mortality in penetrating trauma

Special recognition: This article is dedicated to the memory of Dr. Felix Battistella, a respected investigator and honored colleague.
https://doi.org/10.1016/j.injury.2008.10.015Get rights and content

Abstract

Purpose

Trauma is a significant cause of mortality among elderly patients, with blunt mechanisms accounting for the majority of deaths in this population. Penetrating trauma promises to evolve as an increasingly important aetiology of mortality in the elderly; particularly as the age composition of the overall population continues to shift. Unfortunately, very little data regarding outcomes following penetrating trauma in the elderly exists. The purpose of this study was to define the relationship between age and mortality following penetrating injuries and determine if differences between outcomes of elderly patients sustaining penetrating and blunt trauma exist.

Methods

After IRB approval, we conducted a retrospective trauma registry review at an urban Level 1 trauma centre between January 1, 1998 and December 31, 2005. Demographic, injury, and mortality data for all patients were recorded. The relationship between age and mortality for both blunt and penetrating injuries was examined by comparison of age-specific mortality and relative risk of mortality for both mechanisms at 10 year age intervals. Additionally, the relative risk and 95% confidence interval for mortality in each age group were compared.

Results

There were 26,333 blunt trauma admissions and 8843 penetrating trauma admissions during the 8-year study period. The mortality following both blunt and penetrating trauma remained stable until the age of 55 and increased steadily thereafter. When differences in mortality following blunt and penetrating mechanisms were examined, the overall mortality of penetrating trauma was found to be 2.63 times that of blunt (11.0% vs. 4.2%, RR 2.63; 95% CI: 2.42, 2.85, p < 0.0001). After adjustment for age and other confounding factors, the relative risk of mortality due to penetrating mechanisms was 1.65 (95% CI: 0.88, 2.89, p = 0.10) that of blunt mechanism counterparts. Although statistically higher in penetrating trauma, the relative risk of mortality between penetrating and blunt trauma decreased with increasing age.

Conclusion

The mortality rate with respect to penetrating trauma remains relatively constant until the age of 55, increasing thereafter. When compared to blunt trauma, the relationship between age and mortality in penetrating trauma is similar except that the relative mortality in penetrating trauma is significantly higher for each age group.

Introduction

According to U.S. Census Bureau projections, the age of the American population will continue to mature in the coming decades. In the year 2000, Americans over the age of 45 comprised 34.5% of the population. By the year 2020, this figure is predicted to reach 41.2%. According to 2004 projections, this shift in age demographics is anticipated to continue well into the 21st century.9

While penetrating mechanisms are less common sources of trauma among more elderly members of the population, the number of older individuals sustaining these injuries is likely to increase as the national age demographic evolves. Unfortunately, comparatively less is known about the outcomes of older patients following penetrating trauma than more common blunt mechanisms. Even as understanding of the effects of age-related physiological responses to trauma continues to evolve,4, 5 the relationship between age and outcomes of penetrating trauma remains poorly appreciated.

Section snippets

Patients and methods

After approval from the Institutional Review Board, a retrospective review of the trauma registry at the Los Angeles County+University of Southern California (LAC+USC) Medical Center was performed to identify all trauma patients admitted between January 1, 1998 and December 31, 2005. Demographic and clinical data, including age, gender, injury mechanism, Glasgow Coma Scale (GCS), Injury Severity Score (ISS), Abbreviated Injury Score (AIS) and mortality were obtained and entered into a

Results

During the 8-year period, a total of 35,184 patients were admitted. Of these, 25% sustained penetrating injuries. Individuals older than 55 years represented 3% of the total in the penetrating group and 17% in the blunt group (p < 0.0001). As outlined in Table 1, the penetrating and blunt injury groups also differed significantly for gender, GCS, ISS and AIS. Patients in the penetrating group more often were male (92% vs. 73%, p < 0.0001), had a GCS  8 (11% vs. 9%, p < 0.0001) and an ISS  16 (22% vs.

Discussion

As the population continues to mature, defining the connection between age and trauma outcomes becomes increasingly important. Several investigators have already suggested that this relationship is significant. Finelli et al.,3 in a study comparing the outcomes of trauma victims ≥65 year old to a younger cohort of similarly injured younger patients, found that older patients had markedly higher mortality (27% vs. 14%) and complication rates following major trauma. They also noted that the more

Conclusion

The mortality rate following penetrating trauma is higher than among blunt counterparts at every age interval and rises significantly after age 65. Defining the relationship between age and outcome in penetrating trauma will prove increasingly important as the population ages. An understanding of this relationship will facilitate the refinements of trauma team activation criteria and management protocols that may improve resource allocation and patient outcomes following penetrating injury.

Conflict of interest

The authors have no conflict of interest to report and have received no financial or material support related to this manuscript.

References (10)

  • B.J. Roth et al.

    Penetrating trauma in patients older than 55 years: a case–control study

    Injury

    (2001)
  • F.D. Battistella et al.

    Trauma patients 75 years and older: long-term follow-up results justify aggressive management

    J Trauma

    (1998)
  • D. Demetriades et al.

    Old age as a criterion for trauma team activation

    J Trauma

    (2001)
  • F.C. Finelli et al.

    A case control study for major trauma in geriatric patients

    J Trauma

    (1989)
  • C.A. Kuhne et al.

    Mortality in severely injured elderly trauma patients—when does age become a risk factor?

    World J Surg

    (2005)
There are more references available in the full text version of this article.

Cited by (0)

View full text