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Dialectical Behavior Therapy for Adolescents With Repeated Suicidal and Self-harming Behavior: A Randomized Trial

https://doi.org/10.1016/j.jaac.2014.07.003Get rights and content

Objective

We examined whether a shortened form of dialectical behavior therapy, dialectical behavior therapy for adolescents (DBT-A) is more effective than enhanced usual care (EUC) to reduce self-harm in adolescents.

Method

This was a randomized study of 77 adolescents with recent and repetitive self-harm treated at community child and adolescent psychiatric outpatient clinics who were randomly allocated to either DBT-A or EUC. Assessments of self-harm, suicidal ideation, depression, hopelessness, and symptoms of borderline personality disorder were made at baseline and after 9, 15, and 19 weeks (end of trial period), and frequency of hospitalizations and emergency department visits over the trial period were recorded.

Results

Treatment retention was generally good in both treatment conditions, and the use of emergency services was low. DBT-A was superior to EUC in reducing self-harm, suicidal ideation, and depressive symptoms. Effect sizes were large for treatment outcomes in patients who received DBT-A, whereas effect sizes were small for outcomes in patients receiving EUC. Total number of treatment contacts was found to be a partial mediator of the association between treatment and changes in the severity of suicidal ideation, whereas no mediation effects were found on the other outcomes or for total treatment time.

Conclusion

DBT-A may be an effective intervention to reduce self-harm, suicidal ideation, and depression in adolescents with repetitive self-harming behavior.

Clinical trial registration information—Treatment for Adolescents With Deliberate Self Harm; http://ClinicalTrials.gov/; NCT00675129.

Section snippets

Method

This was a single-blind randomized trial comparing DBT-A with enhanced usual care (EUC). Participants were randomly allocated (Figure 1) to receive either treatment at 1 of the participating child and adolescent psychiatric outpatient clinics in a 1:1 ratio stratified according to gender, presence of major depression, and presence of suicide intent during the most serious episode of self-harm behavior within the 16 weeks before enrollment. Treatment allocation of participants after baseline

Sample Characteristics

Screening, assessment, and randomization procedures leading to allocation of 77 adolescents to either DBT-A (n = 39) or EUC (n = 38) are summarized in Figure 1. Although some patients dropped out of treatment, all patients were followed from baseline to trial completion with no dropouts from the research. Baseline demographic characteristics, diagnostic variables, and pretreatment suicidal and nonsuicidal self-harm behaviors are displayed in Table 1. No significant differences between the

Discussion

This was the first randomized trial of the efficacy of a short version of DBT adapted for the treatment of multi-problem self-harming adolescents with BPD features. Treatment retention in this study was generally good, with no differences between the 2 treatment conditions. DBT was superior to EUC in reducing frequency of self-harm, severity of suicidal ideation, and depressive symptoms, with generally large effect sizes for outcomes in the DBT-A condition, but weak or moderate outcomes in the

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    This article is discussed in an editorial by Dr. Alan Apter on page 1048.

    This article can be used to obtain continuing medical education (CME) at www.jaacap.org.

    Clinical guidance is available at the end of this article.

    The study was funded by grants from the Norwegian Directorate of Health, the South Eastern Regional Health Authority, the ExtraFoundation for Health and Rehabilitation, and the University of Oslo.

    Lien M. Diep, MSc, served as the statistical expert for this research.

    Disclosure: Drs. Mehlum, Ramberg, Haga, Larsson, Stanley, Miller, Sund, Grøholt, and Mss. Tørmoen, Diep, and Laberg report no biomedical financial interests or potential conflicts of interest.

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