Clinical ResearchHeart FailureIncremental Prognostic Significance of Peripheral Endothelial Dysfunction in Patients With Heart Failure With Normal Left Ventricular Ejection Fraction
Heart Failure
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Key Words
endothelial function
heart failure with normal left ventricular ejection fraction
reactive hyperemia-peripheral arterial tonometry
Abbreviations and Acronyms
AHFS
acute heart failure syndrome
BMI
body mass index
BNP
B-type natriuretic peptide
CI
confidence interval
DM
diabetes mellitus
E/e'
ratio of early transmitral flow velocity to tissue Doppler early diastolic mitral annular velocity
eGFR
estimated glomerular filtration rate
HF
heart failure
HFNEF
heart failure with normal left ventricular ejection fraction
HFREF
heart failure with reduced left ventricular ejection fraction
HR
hazard ratio
LV
left ventricular
LVDD
left ventricular diastolic dysfunction
LVEF
left ventricular ejection fraction
NRI
net reclassification index
NT-proBNP
N-terminal pro-B-type natriuretic peptide
NYHA
New York Heart Association
OR
odds ratio
PF5
HFNEF prognostic 5 factors
RHI
reactive hyperemia-peripheral arterial tonometry index
RH-PAT
reactive hyperemia-peripheral arterial tonometry
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Funding: This study was supported in part by a grant-in-aid for Scientific Research (No. C22590786 for S. Sugiyama) from the Ministry of Education, Science, and Culture in Japan. All authors have reported that they have no relationships relevant to the contents of this paper to disclose.
Copyright © 2012 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.