Translational and clinical immunologyAge-associated distribution of normal B-cell and plasma cell subsets in peripheral blood
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E.B. was supported by a grant from Junta de Castilla y León (Fondo Social Europeo, ORDEN EDU/346/2013, Valladolid, Spain). This work was supported by the CB16/12/00400 grant (CIBERONC, Instituto de Salud Carlos III, Ministerio de Economía y Competitividad, Madrid, Spain, and FONDOS FEDER) and the FIS PI12/00905-FEDER grant from the Fondo de Investigaciones Sanitarias of Instituto de Salud Carlos III (Madrid, Spain). O.P. and T.K. were supported by the Ministry of Education, Youth and Sports (NPU I no. LO1604 and 15-28541A). The coordination and innovation processes of this study were supported by the EuroFlow Consortium.
Disclosure of potential conflict of interest: E. Blanco, M. Pérez-Andrés, E. López-Granados, T. Kalina, M. van Zelm, M. van der Burg, J. J. M. van Dongen, and A. Orfao each report being one of the inventors on the EuroFlow-owned patent PCT/NL 2015/050762 (Diagnosis of primary immunodeficiencies), which is licensed to Cytognos, a company that pays royalties to the EuroFlow Consortium. M. van Zelm reports grants from the NHMRC and has a patent issued (EP 2780711 B1). J. J. M. van Dongen and A. Orfao report an Educational Services Agreement from BD Biosciences The rest of the authors declare that they have no relevant conflicts of interest.