ResearchCurrent ResearchMetabolically Obese Normal Weight and Phenotypically Obese Metabolically Normal Youths: The CASPIAN Study
Section snippets
Methods
The study subjects were school children who participated in the baseline survey of the national CASPIAN study. This undergoing multicentric longitudinal study is a joint collaboration of the World Health Organization and the Iranian National Ministries of Health and Education (17, 18). Overall, 4,811 school students (91% participation rate), aged 6 to 18 years, were selected by multistage random cluster sampling from urban and rural areas of six provinces located in diverse parts of the country.
Results
Participants of this multicenter study were 2,248 boys and 2,563 girls, with a mean age of 12.07±3.2 years without significant difference between boys and girls.
The subjects’ characteristics are presented in Table 1, which shows that boys had higher mean levels of weight, height, BMI, waist circumference, SBP, and DBP than girls; other variables were not significantly different in terms of sex. The age group×sex difference was significant for waist circumference and SBP. Other than HDL
Discussion
In this study we found that the prevalence of CVD risk factors and metabolic syndrome was significantly higher in those children with combined obesity than in those with isolated types of obesity. In addition, phenotypically obese metabolically normal subjects were more prevalent in the generalized obesity group. These findings complement some recent observations on adverse health hazards of abnormal central body fat deposition even in childhood. Asian populations are facing an epidemic of
R. Kelishadi is an associate professor of pediatrics and head of the Preventive Pediatric Cardiology Department, and M. A. Ramezani is a community physician, Isfahan University of Medical Sciences, Isfahan, Iran.
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R. Kelishadi is an associate professor of pediatrics and head of the Preventive Pediatric Cardiology Department, and M. A. Ramezani is a community physician, Isfahan University of Medical Sciences, Isfahan, Iran.
S. R. Cook is an assistant professor of pediatrics, Department of Pediatrics, University of Rochester Medical Center, Rochester, NY.
R. Majdzadeh is an associate professor of epidemiology, School of Public Health and Institute of Public Health Research, Tehran University of Medical Sciences, Tehran, Iran.
M. E. Motlagh is an associate professor of pediatrics and director, Bureau of Family Health, M. M. Gouya is an internist and director, Center for Disease Control, and G. Ardalan is a pediatrician and director, School Health Office, Ministry of Health and Medical Education, Tehran, Iran.
M. Motaghian is deputy, Bureau of Health, Ministry of Education and Training, Tehran, Iran.