State-of-the-Art Paper
Percutaneous Interventions for Left Atrial Appendage Exclusion: Options, Assessment, and Imaging Using 2D and 3D Echocardiography

https://doi.org/10.1016/j.jcmg.2015.02.002Get rights and content
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Abstract

Percutaneous left atrial appendage (LAA) exclusion is an evolving treatment to prevent embolic events in patients with nonvalvular atrial fibrillation. In the past few years multiple percutaneous devices have been developed to exclude the LAA from the body of the left atrium and thus from the systemic circulation. Two- and 3-dimensional transesophageal echocardiography (TEE) is used to assess the LAA anatomy and its suitability for percutaneous closure to select the type and size of the closure device and to guide the device implantation procedure in conjunction with fluoroscopy. In addition, 2- and 3-dimensional TEE is also used to assess the effectiveness of device implantation acutely and on subsequent follow-up examination. Knowledge of the implantation options that are currently available along with their specific characteristics is essential for choosing the appropriate device for a given patient with a specific LAA anatomy. We present the currently available LAA exclusion devices and the echocardiographic imaging approaches for evaluation of the LAA before, during, and after LAA occlusion.

Key Words

2D echocardiography
3D echocardiography
left atrial appendage
percutaneous closure

Abbreviations and Acronyms

AF
atrial fibrillation
CMR
cardiac magnetic resonance
LA
left atrium
LAA
left atrial appendage
MDCT
multidetector computed tomography
RT
real time
TEE
transesophageal echocardiography
TTE
transthoracic echocardiography
TS
transseptal

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Dr. Wunderlich has received speaker honoraria from St. Jude Medical and Philips Ultrasound. Dr. Swaans is a proctor for Boston Scientific. Dr. Siegel has received educational funding from Philips Ultrasound. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose. Drs. Wunderlich and Beigel contributed equally to this work.