Original ArticleA Novel Implantation Technique for Pudendal Nerve Stimulation for Treatment of Overactive Bladder and Urgency Incontinence
Section snippets
Material and Methods
This pilot group-study was performed in female and male patients with documented symptoms of OAB with UUI for at least 1 year.
Surgical implantation of the system was performed in 2 stages. The first stage consisted of laparoscopic implantation of an electrode to the pudendal nerve and included a several-week postoperative test screening phase. The second stage included subcutaneous implantation of a generator with the patient under local anesthesia. Laparoscopy was performed with the patient
Results
Fourteen eligible patients (2 men and 12 women) were enrolled. Their mean (SD) age was 46.5 (12.6) years. At the time of evaluation, 3 women were menopausal. All patients in this series received anticholinergic therapy; however, this treatment was stopped because of adverse effects. Sacral neuromodulation had previously failed in 9 patients. Four patients refused further botulinum toxin A injections because of recurrent cystitis and/or need for self-catheterization. Ten patients refused
Discussion
There are many approaches to treatment of OAB, from behavioral changes to medications (antimuscarinic agents), botulinum toxin A injections, and neuromodulation of pelvic nerves. Although pharmacologic therapy is currently the first option for treatment of clinical symptoms of OAB, adherence to treatment is low, in particular because of adverse effects, which lead to discontinuation in 60% of patients [1]. According with the American Urological Association Guideline of May 2012, clinicians may
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The Laparoscopic Implantation of Neuroprosthesis Procedure Increases Leg Lean Mass in Individuals With Paraplegia Due To Traumatic Spinal Cord Injury
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Disclosure: Dr. Possover has a provisional patent pending for an implantation system.