Original ArticleSex Differences in Outcomes and Associated Risk Factors After Acute Ischemic Stroke in Elderly Patients: A Prospective Follow-up Study
Section snippets
Materials and Methods
From January 2009 to December 2011, we recruited consecutive patients with AIS who were hospitalized in the Stroke Unit of Tianjin Medical University General Hospital and Tianjin Haibin People's Hospital, China, within 72 hours after stroke onset. Stroke was defined according to the World Health Organization's criteria, and a diagnosis of AIS was confirmed in all patients based on the evidence of neuroimaging (including computed tomography and magnetic resonance imaging).9 Patients with
Results
During the study period, 871 consecutive AIS patients were hospitalized in the stroke unit of the Tianjin Medical University General Hospital, China. Of these, 750 patients (86.1%) were interviewed in the outpatient department, 60 patients (6.9%) by telephone visiting, and 61 patients (7%) were excluded because they were lost to follow-up at 12 months; 810 patients (93%) were analyzed for outcomes at 12 months. Similarly, 317 patients (71.4%) were interviewed in the outpatient department, 88
Discussion
In the present study, we evaluated sex differences in stroke outcomes and related risk factors at 12 and 36 months after AIS among patients aged 75 years and older in China.
Previous studies have demonstrated significant sex differences in stroke outcomes; women have worse outcomes after stroke compared with men. Women had greater functional impairments at 3 and 12 months after stroke,11, 13, 14 but no sex difference in mortality rate was observed.11 A study from China reported that compared
Conclusions
We assessed the sex differences in stroke outcomes and associated risk factors at 12 and 36 months after stroke in a large hospital-based stroke registry of elderly patients with ischemic stroke in Northern China. LAA and CE (by TOAST classification) were risk factors found to affect mortality, recurrence, and dependency rates in both sexes. However, AF increased the risk of mortality in men and recurrence and dependency in women. Simultaneously, obesity was a protective factor against
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This work was supported partly by Local Key Project of Binhai New District and The Project of Prevention and Treatment System on Cerebrovascular Disease in Dagang Oilfield.