Neuron
Volume 51, Issue 6, 21 September 2006, Pages 678-680
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Leptin in Energy Balance and Reward: Two Faces of the Same Coin?

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Leptin receptors are expressed on mesolimbic dopamine neurons, yet little is known about the functional significance of this anatomical relationship. In this issue of Neuron, Hommel et al. reveal a novel site for leptin's regulation of feeding. In turn, Fulton et al. propose a novel role for leptin in regulating non-feeding-related motivated behaviors.

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