Original articlePopulation-based Incidence of Macular Holes
Section snippets
Materials and Methods
A population-based retrospective chart review was performed for all diagnoses of macular hole between 1992 and 2002 among residents of Olmsted County, Minnesota. Institutional review board approval was obtained for this study. Only patients who provided research authorization according to Minnesota state statues were included, and all work was in accordance with the Health Insurance Portability and Accountability Act of 1996. A search for the diagnosis of macular hole (International
Results
Ninety-four eyes with macular hole in 85 patients met inclusion criteria for the study. Among these, 86 macular holes (91.5%) in 77 patients (90.6%) were idiopathic. Non-idiopathic macular holes were attributed to the following causes: retinal detachment repair (3), secondary to trauma (2), macular translocation surgery (1), unspecified eye surgery (1), and chronic inflammation (1) (Table 1).
Discussion
The age- and sex-adjusted overall incidence of macular holes in Olmsted County, Minnesota, between 1992 and 2002, was found to be 9.38 eyes per 100,000 population per year. Idiopathic macular holes were found to have an incidence of 8.69 eyes per 100,000 population per year.
Currently available epidemiologic information about macular holes focuses on prevalence and varies widely. In the Beaver Dam Eye Study, macular hole prevalence was 2.9 per 1000 (Moss SE, Klein R, personal communication,
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2023, Archivos de la Sociedad Espanola de OftalmologiaSpontaneous closure of an idiopathic macular hole after epiretinal membrane development
2023, American Journal of Ophthalmology Case ReportsCitation Excerpt :The reported prevalence is 0.2/1000 in Australia and 3.3/1000 in the United States.3,4 FTMHs are usually unilateral and tend to affect women more frequently between the sixth and seventh decade of life.2 A diagnosis of FTMH is based on clinical examination and confirmed by optical coherence tomography (OCT).5
Manuscript no. 2008-162.
Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article.
Funded in part by Research to Prevent Blindness, Inc., and the Mayo Foundation for Medical Education and Research. The sponsor or funding organization had no role in the design or conduct of this research.