ROS and the DNA damage response in cancer
Under a Creative Commons license
open access
Abbreviation
AML
Acute myeloid leukemia
ATM
Ataxia telangiectasia mutated
ATR
Ataxia telangiectasia mutated and Rad3 related
ATRIP
ATR interacting protein
BSO
Buthionine sulfoximine
BER
Base excision repair
Cdc25
Cell division cycle 25
DDR
DNA damage response
DNA PK
DNA-dependent protein kinase
dNTP
deoxyribonucleotide triphosphate
DSB
Double strand break
ETC
Electron transport chain
H2O2
Hydrogen peroxide
HER-2
human epidermal growth factor receptor 2
HR
Homologous recombination
ICD
Immunogenic cell death
MAPK
Mitogen-activated protein kinases
Mdm2
Mouse double minute 2
MRN
Mre11-Rad50-Nbs1
mtROS
Mitochondrial ROS
NADPH
Nicotinamide adenine dinucleotide phosphate
NCF2
Neutrophil Cytosolic Factor 2
NHEJ
Non-homologous end joining
NRF-2
Nuclear factor (erythroid-derived 2)-like 2
OXPHOS
Oxidative phosphorylation
PLK1
Polo-like kinase 1
PPP
Pentose phosphate pathway
ROS
Reactive oxygen species
RPA
Replication protein A
SOD
Superoxide dismutase
XRCC4
X-ray repair cross-complementing protein 4
Keywords
Reactive Oxygen Species
ROS
DNA damage response
DDR
Chemotherapy
Radiotherapy
Cited by (0)
- 1
Equal contributions.
© 2018 The Authors. Published by Elsevier B.V.