Original articleLaparoscopic gastric plication for treatment of severe obesity
Section snippets
Methods
The present study was a prospective, nonrandomized feasibility study of 2 gastric plication techniques. The institutional review board approved the present study, and the patients were screened and recruited for enrollment from our standard outpatient population. The study was registered with www.clinicaltrials.gov (clinicaltrials.gov identifier NCT00721227) before patient enrollment. The consent process was conducted by a research nurse coordinator assigned to the study full time and
Results
A total of 15 patients (3 men) were enrolled in the present study. Their mean age was 42 years (range 26–58), and the average preoperative BMI was 43.3 ± 4.1 kg/m2 (range 36.9–49.0). No significant differences were present in age or BMI between the AP and GCP groups.
The mean procedure duration for the AP group was 89 minutes (range 68–147). Of the 9 patients in the AP group, 2 required 3 rows of sutures to complete the procedure and 7 required 2 rows of sutures to complete the procedure.
The
Discussion
The field of bariatric surgery is continually evolving. Since the introduction of surgical procedures to induce weight loss, many different operations have been tried and abandoned owing to the poor long-term weight loss and/or metabolic or mechanical complications. During the past decade, the use of sleeve gastrectomy has gained popularity, and it has become widely accepted as a primary bariatric operation, as well as a first-stage operation for high-risk patients. Five-year data are now
Conclusion
Our initial experience has suggested that a reduction in gastric capacity can be achieved using plication of either the anterior stomach or greater curvature. The early weight loss results were encouraging, with better weight loss for the patients who underwent GCP. GCP is promising from a risk/benefit standpoint and warrants additional investigation. A multicenter prospective trial is ongoing.
Disclosures
S. A. Brethauer, M. Kroh, and P. R. Schauer are consultants and speakers for Ethicon Endo-Surgery, and J. L. Harris is an engineer for Ethicon Endo-Surgery and contributed to the protocol and technique development and data analysis.
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