Original articleGastrointestinal function and eating behavior after gastric bypass and duodenal switch
Section snippets
Methods
The present study was conducted at Oslo University Hospital Aker (Oslo, Norway) and Sahlgrenska University Hospital (Gothenburg, Sweden). The study design, inclusion and exclusion criteria, a study flow diagram, and detailed descriptions of the operations have been previously reported [7], [8], [10]. The appropriate local ethics committees approved the study protocol, which was registered at http://ClinicalTrials.gov (registration number NCT00327912).
Results
No significant differences were found between the 2 groups in any outcome measure at baseline.
Discussion
In the present 2-year randomized trial, duodenal switch was associated with more symptoms of diarrhea, more frequent defecations at daytime, and more anal leakage of stool than was gastric bypass. The changes in the other gastrointestinal symptoms and bowel habits, eating behavior, caloric intake, and psychosocial functioning were broadly similar between the procedures. Thus, patients with severe obesity choosing gastric bypass or duodenal switch should be informed about the potential
Conclusion
Both gastric bypass and duodenal switch were associated with gastrointestinal side effects, but these symptoms were more pronounced after the duodenal switch. Psychosocial function improved similarly, and both groups had significant reductions in uncontrolled and emotional eating and a reduced mean total caloric intake.
Disclosures
The authors have no commercial associations that might be a conflict of interest in relation to this article.
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Supported by research grants from the South-Eastern Norway Regional Health Authority and Sahlgrenska University Hospital.