Integrated health articleDiet-induced thermogenesis and respiratory quotient after Roux-en-Y gastric bypass
Section snippets
Methods
The project was approved by the Ethics Committee of the Faculty of Health of the University of Brasilia (Brasilia, Brazil; DF 017/11). The present study was registered as a clinical trial (protocol number NCT01396460).
The present study was a cross-sectional study. The participants were patients of the Gastrocirurgia de Brasilia Clinic (Brasilia, Brazil). All participants signed an informed consent form. They were separated into 2 groups: patients who had undergone RYGB ≥12 months previously
Results
The population consisted of 69 patients, 35 of whom were clinically severe obese patients (control group) and 34 of whom had undergone RYGB surgery ≥12 months previously (RYGB group). The mean age of the RYGB group was 40.6 ± 10.0 years and of the control group was 36.5 ± 7.0 years. In both groups, most of the subjects were women (Table 1).
After a 12-hour fasting period and also after consuming a standard meal of 200 mL of coconut water and a chicken salad sandwich on whole wheat bread, the
Discussion
RYGB results in rapid and long-term sustainable weight loss in >90% of cases [17], [18]. Complex mechanisms involving communication between the GIT and various organs contribute to such weight loss and to an improvement in several co-morbidities associated with obesity. Changes in the amount of food eaten and the structure of the GIT appear to cause changes in its function and cause it to emit signals to the brain, liver, skeletal muscle, adipose tissue, and pancreas, thereby determining the
Conclusion
The RYGB patients presented with greater DIT than the control group. This could be 1 of the mechanisms that contributes to making this surgical procedure the most effective for losing weight and maintaining weight loss in the long term. RYGB can improve postprandial use of carbohydrates, such as was seen in the RQ increase among the RYGB group.
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Cited by (32)
Metabolic profiles, energy expenditures, and body compositions of the weight regain versus sustained weight loss patients who underwent Roux-en-Y gastric bypass
2021, Surgery for Obesity and Related DiseasesCitation Excerpt :DIT is the energy expended in the digestion, absorption, and storage of nutrients from food. A recent study showed that DIT increased significantly (200%) in patients who underwent RYGB (for at least 1 year after surgery) compared with individuals with obesity [57]. Protein consumption is known to be a contributing factor to increased DIT.
Thermic effect of food and resting energy expenditure after sleeve gastrectomy for weight loss in adolescent females
2020, Surgery for Obesity and Related DiseasesCitation Excerpt :Studies of energy metabolism after RYGB are more abundant, with several showing an increase in REE per kilogram weight after surgery [11,33–35], while others noted no change [14,36]. While no data have been published about TEF or RQ after SG, there are several studies of TEF in participants with RYGB, also with mixed results [13,14,37,38]. Two controlled, cross-sectional studies found that participants who were at least 1 year post RYGB had a higher TEF and RQ compared with those with and without obesity [13,38].
Accuracy of total energy expenditure predictive equations after a massive weight loss induced by bariatric surgery
2018, Clinical Nutrition ESPENDiet-induced thermogenesis in postoperatve Roux-en-Y gastric bypass patients with weight regain
2016, Surgery for Obesity and Related Diseases
Supported by Gastrocirurgia, Brasília, Brazil.