Original articleEffects of a very low calorie diet in the preoperative stage of bariatric surgery: a randomized trial☆
Section snippets
Methods
This clinical study was a randomized, open-label trial that was performed with patients who were preparing for a RYGB bariatric surgical procedure. This study was approved by the Ethics Committee of the Faculty of Health Services at the University of Brasilia (no. 160/09) and registered in Clinical Trials (NCT01748682). All participants signed an informed consent form.
The intervention period lasted 14 days. Fifteen days before surgery, patients were randomly selected to follow a liquid diet
Results
Of the 240 participants who were invited, 142 accepted the invitation to participate in the study and were randomly divided into 2 groups of 71 patients each. Of these 142 patients, 21 did not perform one of the US abdominal tests (13 patients of the ND group and 8 of the LD group), and 13 did not undergo blood tests (4 from the LD group and 9 from the ND group) at one of the evaluation moments and, thus, were excluded from the study population. Four other patients withdrew from participating
Discussion
The present study showed that both diets were effective in reducing weight in clinically severe obese patients in the preop stage of bariatric surgery. Volunteers from both groups lost weight, however, LD group performed better than the ND diet. Besides, patients who received LD presented a decrease in visceral fat and decreased surgical time.
The study by Riess et al. [6] found no association between preop weight loss and the duration of surgery or hospital stay. In their study, only some
Conclusion
The use of a VLCD in the preoperative period of bariatric surgery is safe and effective. The patients who followed the LD had greater overall fat loss and a notable decrease in visceral fat, along with a consequent reduction in the duration of surgery time. The use of LD has presented greater overall weight loss and a more rapid decrease in blood glucose compared with the ND.
The VLCD seems to be an important tool for the improvement of biochemical parameters among patients with clinically
Disclosures
The authors have no commercial associations that might be a conflict of interest in relation to this article.
References (28)
- et al.
Effect of preoperative weight loss on laparoscopic gastric bypass outcomes
Surg Obes Relat Dis
(2008) - et al.
Effectiveness of the US Department of Agriculture 5-step multiple-pass method in assessing food intake in obese and nonobese women
Am J Clin Nutr
(2003) - et al.
Soup preloads in a variety of forms reduce meal energy intake
Appetite
(2007) - et al.
Short-term weight loss and hepatic triglyceride reduction: evidence of a metabolic advantage with dietary carbohydrate restriction
Am J Clin Nutr
(2011) Resistance to ketonuria and ketosis in obese subjects
Am J Clin Nutr
(1974)- et al.
Sugar-sweetened beverages and weight gain in children and adults: a systematic review and meta-analysis
Am J Clin Nutr
(2013) - et al.
Liquid calories, sugar, and body weight
Am J Clin Nutr
(2007) - et al.
Biological effects of bariatric surgery on obesity-related comorbidities
Can J Surg
(2013) Pesquisa de Orçamentos Familiares 2008–2009
Antropometria e Estado Nutricional de Crianças, Adolescentes e Adultos no Brasil
(2010)- et al.
Metabolic/Bariatric surgery worldwide 2011
Obes Surg
(2013)
Nutritional Considerations after bariatric surgery
Critical Care Nurse
Factors determining conversion from laparoscopic to open Roux-en-Y gastric bypass
Obes Surg
An evidenced-based assessment of preoperative weight loss in bariatric surgery
Obes Surg
Use of very low-energy diet in preoperative weight loss: efficacy and safety
Obes Res
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Supported by Gastrocirurgica Clinic, Brasilia, Brazil, the University of Brasilia, Sabin laboratory and Essential Pharmacy Compounding Laboratory.