American Association of Endocrine SurgeonsImproved preoperative planning for directed parathyroidectomy with 4-dimensional computed tomography
Section snippets
Methods
For the purposes of this paper, standard definitions of commonly used terms have been incorporated into Table I.
Patients
Demographic and laboratory data are provided in Table II. The median age of patients at diagnosis was 60 years (range, 27-83 years), and the female-to-male ratio was 5.3 to 1. The median patient weight was 79.5 kg (range, 41.4-162.0 kg), and the median BMI was 29.5 kg/m2 (range 17.8-67.4 kg/m2). The median preoperative serum calcium level was 10.9 mg/dL (range, 9.7-16.0 mg/dL; normal, 8.4-10.2 mg/dL). The median preoperative PTH level was 118 pg/mL (range, 60-524 pg/mL; normal, 10-65 pg/mL).
Discussion
Most studies in the literature that address parathyroid imaging report the ability of an imaging modality to localize (lateralize) parathyroid tumors to the correct side of the neck.6, 9, 10, 11, 12, 13, 14 Sensitivity for lateralization by ultrasonography varies from 61% to 88%,6, 9, 10, 11, 12, 13, 14 whereas sensitivity for lateralization by sestamibi varies from 68% to 86%.6, 9, 10, 12, 13 Using lateralization to measure the performance of preoperative imaging modalities in the current
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Supported in part by research funds from the Hamill Foundation and from the Department of Diagnostic Radiology at The University of Texas M.D. Anderson Cancer Center.