Letter to the Editors-in-ChiefSensitivity of discharge diagnosis ICD-9 codes for pediatric venous thromboembolism is greater than specificity, but still suboptimal for surveillance and clinical research
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Conflict of interest
The authors have no relevant conflicts of interest to disclose.
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Cited by (19)
Catheter-Related Venous Thrombosis in Hospitalized Pediatric Patients with Inflammatory Bowel Disease: Incidence, Characteristics, and Role of Anticoagulant Thromboprophylaxis with Enoxaparin
2018, Journal of PediatricsCitation Excerpt :In contrast, venous thrombotic events in prior studies were identified retrospectively using International Classification of Diseases hospital discharge codes. Owing to low accuracy, the identification of venous thrombosis using discharge International Classification of Diseases codes is suboptimal in surveillance efforts and in the clinical research of pediatric VTE.24,25 Moreover, several studies have suggested that PICCs are associated with a higher risk of catheter-related thrombosis than are other CVCs.26-28
Development of a new risk score for hospital-associated venous thromboembolism in noncritically ill children: Findings from a large single-institutional case-control study
2014, Journal of PediatricsCitation Excerpt :Previous studies have largely neglected, or have not been sufficiently powered to achieve, risk models specifically applicable to each of these subpopulations. An additional strength of the present study is its use of diagnostic validation of ICD-9 discharge code-based VTE case definition via the radiologic record, seldom used in previous studies that have evaluated pediatric HA-VTE risk factors.13,19 The HA-VTE risk factors determined in this study for noncritically ill hospitalized children are concordant with recent work by Branchford et al13 in an independent hospitalized pediatric population, with respect to identification of infection and LOS as significant independent risk factors for HA-VTE in children.
Incidence of thrombosis in children with tunneled central venous access devices versus peripherally inserted central catheters (PICCs)
2013, Thrombosis ResearchCitation Excerpt :There are several limitations to this study. First, the study relies on an deidentified hospital discharge database whereby the presence of the types of lines and DVT as well as the other diagnoses (CCC) were determined by ICD-9 coding and it is known that such coding can be inaccurate [13]. Second, while the database listed the top 20 diagnoses for each subject, it is possible that a diagnosis of DVT was not included if a child had more than 20 diagnoses listed for an admission underestimating the overall incidence of DVT.