Strides in TransplantationKidney transplantationSlow Progression of Aortic Calcification Is a Potential Benefit of Pre-emptive Kidney Transplantation
Section snippets
Study Design
We conducted a retrospective cohort study of recipients of kidney transplantations at 2 centers. This study was conducted in accordance with the ethical standards of the Declaration of Helsinki and approved by the ethical committee of Hirosaki University Graduate School of Medicine (authorization number: 2017-089). For this type of retrospective study, formal consent was not required.
Study Population
In this study, we included 100 consecutive kidney transplantation cases that were performed in Hirosaki
Results
Median age and median follow-up periods of this cohort were 45 years and 52.1 months, respectively. Table 1 lists the clinical characteristics of the patients enrolled in the study. The median age was significantly lower in PKT recipients (47 vs 38 years, P = .044). The number of living kidney transplantation was significantly greater in the PKT group. Preoperative eGFR was significantly higher in PKT recipients (Fig 1A). Postoperative eGFR did not significantly differ between the groups (Fig 1
Discussion
In the present study, we showed aortic calcification and ACI progression rate were significantly higher in non-PKT recipients than in PKT recipients. To the best of our knowledge, this is the first report to demonstrate the association between PKT and aortic calcification. Several studies have addressed the clinical importance of vascular calcification among dialysis patients [6], [10]; however, only a few studies have demonstrated implication of aortic calcification in renal transplant
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Living Kidney Transplantation From Marginal Donors Presents Feasible Donor Renal Function Despite Inferior Recipient Renal Function
2020, Transplantation ProceedingsCitation Excerpt :On the other hand, donor age (P < .001) and donor CCr (P = .001) were selected as predictive factors for the donor postoperative eGFR (Table 3, lower rows). Although significant evidence of kidney transplantation has been accumulated [16–21], the number of transplantations is limited by various factors in many countries. There is an increasing organ shortage problem for kidney transplantation in Japan because of the absence of an organ exchange program and the small number of cadaveric donations [2,5].
Impact of distance between donor and recipient hospitals on cadaveric kidney transplantation outcomes
2019, Clinical and Experimental Nephrology
This work was supported by a Grant-in-Aid for Scientific Research (No. 15H02563 15K15579, 17K11118, 17K11119, 17K16768, 17K16770, and 17K16771) from the Japan Society for the Promotion of Science.