Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology
Oral and Maxillofacial PathologyOsteogenic sarcoma of the jaw bones: A single institution experience over a 21-year period
Section snippets
Materials and methods
All cases that were histologically diagnosed as osteosarcoma of the jaws from January 1983 to December 2003 were retrieved from the records of the Departments of Oral Pathology and Biology and Oral and Maxillofacial Surgery of the Lagos University Teaching Hospital, Lagos, Nigeria. The histologic slides were reevaluated by one of the authors with a view to classifying the lesions. All the cases were subjected to analysis of age, gender, and symptoms at presentation, as well as site of
Results
Out of 2,830 biopsies of oral and jaw lesions diagnosed between January 1983 and December 2003, 59 (2.08%) were primary malignant bone tumors of the jaws, of which osteosarcoma is the most frequently occurring, accounting for 28.8% (Table I). Other malignant bone tumors of the jaws are as shown on Table I. Of these biopsies of oral and jaw lesions, 17 (0.6%) were osteogenic sarcomas (OS). The mean (±SD) age of patients with OS at presentation was 27.2 ± 13.6 years (range 11-70 years). Five
Discussion
Worldwide, OS is considered to be a rare lesion occurring in about 1 per 100,000 persons per year; about 6% to 7% of all OS occur in the maxillofacial region.4, 14 The incidence of OS is not well established in Nigerians, and few reports from Nigeria are found in the literature.11, 12, 13 OS of the head and neck is considered by most clinicians to be distinct from OS that arises in the long bones. It is reported to affect older patients and follows a different clinical pattern.6, 7, 8, 9, 15, 16
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2014, Journal of Oral and Maxillofacial Surgery, Medicine, and PathologyCitation Excerpt :Osteoblastic variant is the most frequent histological type in our study followed by chondroblastic variant. This is in accordance with some [2,66] but not most of prior studies in which the chondroblastic subtype was predominant [34,55,57,67]. Huvos et al. [68] found the fibroblastic to be most common.