Case reportBilateral metastatic renal synovial sarcoma
Section snippets
Case report
A 51-year-old woman presented with radiographic findings of bilateral renal masses diagnosed by surveillance computed tomography scans. She was originally diagnosed at age 28 with synovial sarcoma of the left forearm for which she underwent above the elbow amputation. This was followed by multidrug chemotherapy. She developed her first pulmonary metastasis at 5 years postoperatively, experiencing recurrence-free intervals of 2 to 5 years after each serial pulmonary resection. She was again
Comment
Synovial sarcomas account for 6% to 10% of soft-tissue sarcomas, and most of these arise in the extremities. Synovial sarcomas have been known to arise in many diverse tissue types, including the kidney.1, 2 The natural history of this tumor is that of local recurrence. Eventual metastasis is common, with the lungs the most common site, up to 80% in some series, followed by dissemination to the bones and bone marrow.3 We report an uncommon pattern of metastasis involving bilateral renal
References (3)
- et al.
Primary synovial sarcoma of the kidneyreport of a case confirmed by molecular detection of the SYT-SSX2 fusion transcripts
Pathol Int
(2001)