Elsevier

Urology

Volume 98, December 2016, Pages 1-3
Urology

Commentary
Commentary: Does Asymptomatic Bacteriuria Reduce the Risk of Recurrence of Non–muscle-invasive Bladder Tumors?

https://doi.org/10.1016/j.urology.2016.07.033Get rights and content

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Comment

In these 2 cohorts of patients at high risk of recurrent NMIBC, those with chronic ABU had fewer recurrences, fewer numbers of recurrent tumors, and longer tumor-free survival times than similarly staged uninfected patients, leading us to hypothesize that bacteriuria may have a biologic effect in reducing the risk of recurrence. A mechanism to explain how this might occur is unknown, but one possibility is that chronic bacteriuria may act similarly to BCG in inducing a local immune response

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