Elsevier

Vision Research

Volume 45, Issue 19, September 2005, Pages 2549-2563
Vision Research

Pupillary evaluation of retinal asymmetry: Development and initial testing of a technique

https://doi.org/10.1016/j.visres.2005.04.003Get rights and content
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Abstract

Glaucomatous damage to upper and lower retina is often unequal. We have developed a rapid, objective, quantitative measure of asymmetry of retinal sensitivity, using infrared pupillometry and pairs of large stimuli that are symmetric about the horizontal meridian. Results for a group of 11 young subjects free of eye disease indicate that the distribution of asymmetry is close to a normal distribution centered near upper/lower symmetry. Some subjects showed modest amounts of asymmetry, which was relatively uniform within each eye, and between the two eyes, of the subject. This approach to determination of asymmetry within an eye is potentially applicable to testing patients with glaucoma. The narrowness of the distribution should make it possible to detect asymmetries caused by disease.

Keywords

Pupillary light reflex
RAPD
Retina
Human

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