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Direct numerical simulation of stenotic flows. Part 1. Steady flow

Published online by Cambridge University Press:  14 June 2007

SONU S. VARGHESE
Affiliation:
School of Mechanical Engineering, Purdue University, 585 Purdue Mall, West Lafayette, IN 47907, USA
STEVEN H. FRANKEL
Affiliation:
School of Mechanical Engineering, Purdue University, 585 Purdue Mall, West Lafayette, IN 47907, USA
PAUL F. FISCHER
Affiliation:
Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439, USA

Abstract

Direct numerical simulations (DNS) of steady and pulsatile flow through 75% (by area reduction) stenosed tubes have been performed, with the motivation of understanding the biofluid dynamics of actual stenosed arteries. The spectral-element method, providing geometric flexibility and high-order spectral accuracy, was employed for the simulations. The steady flow results are examined here while the pulsatile flow analysis is dealt with in Part 2 of this study. At inlet Reynolds numbers of 500 and 1000, DNS predict a laminar flow field downstream of an axisymmetric stenosis and comparison to previous experiments show good agreement in the immediate post-stenotic region. The introduction of a geometric perturbation within the current model, in the form of a stenosis eccentricity that was 5% of the main vessel diameter at the throat, resulted in breaking of the symmetry of the post-stenotic flow field by causing the jet to deflect towards the side of the eccentricity and, at a high enough Reynolds number of 1000, jet breakdown occurred in the downstream region. The flow transitioned to turbulence about five diameters away from the stenosis, with velocity spectra taking on a broadband nature, acquiring a -5/3 slope that is typical of turbulent flows. Transition was accomplished by the breaking up of streamwise, hairpin vortices into a localized turbulent spot, reminiscent of the turbulent puff observed in pipe flow transition, within which r.m.s. velocity and turbulent energy levels were highest. Turbulent fluctuations and energy levels rapidly decayed beyond this region and flow relaminarized. The acceleration of the fluid through the stenosis resulted in wall shear stress (WSS) magnitudes that exceeded upstream levels by more than a factor of 30 but low WSS levels accompanied the flow separation zones that formed immediately downstream of the stenosis. Transition to turbulence in the case of the eccentric stenosis was found to be manifested as large temporal and spatial gradients of shear stress, with significant axial and circumferential variations in instantaneous WSS.

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Papers
Copyright
Copyright © Cambridge University Press 2007

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References

REFERENCES

Abdallah, S. A. & Hwang, N. H. C. 1988 Arterial stenosis murmurs: An analysis of flow and pressure fields. J. Acoust. Soc. Am. 83, 318334.CrossRefGoogle ScholarPubMed
Ahmed, S. A. & Giddens, D. P. 1983 a Velocity measurements in steady flow through axisymmetric stenoses at moderate Reynolds number. J. Biomech. 16, 505516.CrossRefGoogle Scholar
Ahmed, S. A. & Giddens, D. P. 1983 b Flow disturbance measurements through a constricted tube at moderate Reynolds numbers. J. Biomech. 16, 955963.CrossRefGoogle ScholarPubMed
Ahmed, S. A. & Giddens, D. P. 1984 Pulsatile poststenotic flow studies with laser Doppler anemometry. J. Biomech. 17, 695705.CrossRefGoogle ScholarPubMed
Bathe, M. & Kamm, R. 1999 A fluid structure interaction finite element analysis of pulsatile blood flow through a compliant stenotic artery. J. Biomech. Engng 121, 361369.CrossRefGoogle ScholarPubMed
Berger, S. & Jou, L.-D. 2000 Flows in stenotic vessels. Annu. Rev. Fluid Mech. 32, 347382.CrossRefGoogle Scholar
Buchanan, J. Jr., Kleinstreuer, C. & Comer, J. 2000 Rheological effects on pulsatile hemodynamics in a stenosed tube. Computers Fluids 29, 695724.CrossRefGoogle Scholar
Cassanova, R. A. & Giddens, D. P. 1978 Disorder distal to modeled stenoses in steady and pulsatile flow. J. Biomech. 11, 441453.CrossRefGoogle ScholarPubMed
Clark, C. 1980 The propagation of turbulence produced by a stenosis. J. Biomech. 13, 591604.CrossRefGoogle ScholarPubMed
Deshpande, M. D. & Giddens, D. P. 1980 Turbulence measurements in a constricted tube. J. Fluid Mech. 97, 6589.CrossRefGoogle Scholar
Deville, M. O., Fischer, P. F. & Mund, E. H. 2002 High-Order Methods for Incompressible Fluid Flow. Cambridge University Press.CrossRefGoogle Scholar
Eliahou, S., Tumin, A. & Wygnanski, I. 1998 Laminar-turbulent transition in Poiseuille pipe flow subjected to periodic perturbation emanating from the wall. J. Fluid Mech. 361, 333349.CrossRefGoogle Scholar
Fischer, P. F. 1997 An overlapping Schwarz method for spectral element solution of the incompressible Navier-Stokes equations. J. Comput. Phys. 133, 84101.CrossRefGoogle Scholar
Fischer, P. F., Kruse, G. & Loth, F. 2002 Spectral element methods for transitional flows in complex geometries. J. Sci. Comput. 17, 8198.CrossRefGoogle Scholar
Fischer, P. F. & Mullen, J. 2001 Filter-based stabilization of spectral element methods. C. R. l'Acad. Sci. Paris I 332, 265270.CrossRefGoogle Scholar
Fredberg, J. J. 1974 Origin and character of vascular murmurs: Model studies. J. Acoust. Soc. Am. 61, 10771085.CrossRefGoogle Scholar
Han, G., Tumin, A. & Wygnanski, I. 2000 Laminar-turbulent transition in Poiseuille pipe flow subjected to periodic perturbation emanating from the wall. Part 2. Late stage of transition. J. Fluid Mech. 419, 127.CrossRefGoogle Scholar
He, S. & Jackson, J. 2000 A study of turbulence under conditions of transient flow in a pipe. J. Fluid Mech. 408, 138.CrossRefGoogle Scholar
Hinze, J. O. 1975 Turbulence. McGraw-Hill.Google Scholar
Jeong, J. & Hussain, F. 1995 On the identification of a vortex. J. Fluid Mech. 285, 6994.CrossRefGoogle Scholar
Khalifa, A. M. A. & Giddens, D. P. 1981 Characterization and evolution of post-stenotic flow disturbances. J. Biomech. 14, 279296.CrossRefGoogle Scholar
Kim, B. M. & Corcoran, W. H. 1974 Experimental measurements of turbulence spectra distal to stenoses. J. Biomech. 7, 335342.CrossRefGoogle ScholarPubMed
Klebanoff, P. S., Tidstrom, K. D. & Sargent, L. M. 1962 The three-dimensional nature of boundary layer instability. J. Fluid Mech. 12, 134.CrossRefGoogle Scholar
Ku, D. N. 1997 Blood flow in arteries. Annu. Rev. Fluid Mech. 29, 399434.CrossRefGoogle Scholar
Lieber, B. B. & Giddens, D. P. 1988 Apparent stresses in disturbed pulsatile flows. J. Biomech. 21, 287298.CrossRefGoogle ScholarPubMed
Lieber, B. B. & Giddens, D. P. 1990 Post-stenotic core flow behavior in pulsatile flow and its effects on wall shear stress. J. Biomech. 23, 597605.CrossRefGoogle ScholarPubMed
Lu, P. C., Gross, D. R. & Hwang, N. H. C. 1980 Intravascular pressure and velocity fluctuations in pulmonic arterial stenosis. J. Biomech. 13, 291300.CrossRefGoogle ScholarPubMed
Lu, P. C., Hui, C. N. & Hwang, N. H. C. 1983 A model investigation of the velocity and pressure spectra in vascular murmurs. J. Biomech. 16, 923931.CrossRefGoogle Scholar
Lusis, A. J. 2000 Atherosclerosis. Nature 407, 233241.CrossRefGoogle ScholarPubMed
Maday, Y., Patera, A. T. & Rønquist, E. M. 1990 An operator-integration-factor splitting method for time-dependent problems: Application to incompressible fluid flow. J. Sci. Comput. 5, 263292.CrossRefGoogle Scholar
Mallinger, F. & Drikakis, D. 2002 Instability in three-dimensional unsteady stenotic flows. Intl J. Heat Fluid Flow 23, 657663.CrossRefGoogle Scholar
Mittal, R., Simmons, S. P. & Najjar, F. 2003 Numerical study of pulsatile flow in a constricted channel. J. Fluid Mech. 485, 337378.CrossRefGoogle Scholar
Ojha, M., Cobbold, C., Johnston, K. & Hummel, R. 1989 Pulsatile flow through constricted tubes: An experimental investigation using photochromic tracer methods. J. Fluid Mech. 13, 173197.CrossRefGoogle Scholar
Priymak, V. G. & Miyazaki, T. 2004 Direct numerical simulation of equilibrium spatially localized structures in pipe flow. Phys. Fluids 16, 42214234.CrossRefGoogle Scholar
Ryval, J., Straatman, A. G. & Steinman, D. A. 2004 Two-equation turbulence modeling of pulsatile flow in a stenosed tube. J. Biomech. Engng 126, 625635.CrossRefGoogle Scholar
Scotti, A. & Piomelli, U. 2001 a Numerical simulation of pulsating turbulent channel flow. Phys. Fluids 13, 13671384.CrossRefGoogle Scholar
Scotti, A. & Piomelli, U. 2001 b Turbulence models in pulsating flow. AIAA Paper 010729.Google Scholar
Shan, H., Ma, B., Zhang, Z. & Nieuwstadt, F. T. M. 1999 Direct numerical simulation of a puff and a slug in transitional cylindrical pipe flow. J. Fluid Mech. 387, 3960.CrossRefGoogle Scholar
Sherwin, S. J. & Blackburn, H. M. 2005 Three-dimensional instabilities and transition of steady and pulsatile axisymmetric stenotic flows. J. Fluid Mech. 533, 297327.CrossRefGoogle Scholar
Stroud, J., Berger, S. & Saloner, D. 2000 Influence of stenosis morphology on flow through severely stenotic vessels: Implications for plaque rupture. J. Biomech. 33, 443455.CrossRefGoogle ScholarPubMed
Tang, D., Yang, J., Yang, C. & Ku, D. 1999 A nonlinear axisymmetric model with fluid-wall interactions for steady viscous flow in stenotic elastic tubes. J. Biomech. Engng 121, 494501.CrossRefGoogle ScholarPubMed
Tennekes, H. & Lumley, J. L. 1972 A First Course in Turbulence. MIT Press.CrossRefGoogle Scholar
Varghese, S. S. & Frankel, S. H. 2003 Numerical modeling of pulsatile turbulent flow in stenotic vessels. J. Biomech. Engng 125, 445460.CrossRefGoogle ScholarPubMed
Varghese, S. S., Frankel, S. H. & Fischer, P. F. 2007 Direct numerical simulation of stenotic flows. Part 2. Pulsatile flow. J. Fluid Mech. 582, 281318.CrossRefGoogle Scholar
Welch, P. D. 1967 The use of fast Fourier transform for the estimation of power spectra: A method based on time averaging over short modified periodograms. IEEE Trans. Audio Electroacousti. AU 15, 7073.CrossRefGoogle Scholar
Wilcox, D. 1993 Turbulence Modeling for CFD. La Cañada, California, CA: DCW Industries.Google Scholar
Winter, D. C. & Nerem, R. M. 1984 Turbulence in pulsatile flows. Ann. Biomed. Engng 12, 357369.CrossRefGoogle ScholarPubMed
Womersley, J. R. 1955 Method for the calculation of velocity, rate of flow and viscous drag in arteries when the pressure gradient is known. J. Physiol. 127, 553563.CrossRefGoogle ScholarPubMed
Wootton, D. M. & Ku, D. N. 1999 Fluid mechanics of vascular systems, diseases, and thrombosis. Annu. Rev. Biomed. Engng 1, 299329.CrossRefGoogle ScholarPubMed
Wygnanski, I. J. & Champagne, F. H. 1973 On transition in a pipe. Part 1. The origin of puffs and slugs and the flow in a turbulent slug. J. Fluid Mech. 59, 281335.CrossRefGoogle Scholar
Wygnanski, I. J., Sokolov, M. & Friedman, D. 1975 On transition in a pipe. Part 2. The equilibrium puff. J. Fluid Mech. 69, 283304.CrossRefGoogle Scholar
Young, D. F. 1979 Fluid mechanics of arterial stenosis. J. Biomech. Engng 101, 157173.CrossRefGoogle Scholar
Young, D. F. & Tsai, F. Y. 1979 a Flow characteristics in models of arterial stenoses – I steady flow. J. Biomech. Engng 6, 395410.CrossRefGoogle Scholar
Young, D. F. & Tsai, F. Y. 1979 b Flow characteristics in models of arterial stenoses – II unsteady flow. J. Biomech. Engng 6, 547559.CrossRefGoogle Scholar