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Olfactory bulb volume and olfactory sulcus depth in patients with Behçet's disease

Published online by Cambridge University Press:  18 December 2018

A Doğan ,
N Bayar Muluk ,
N Asal ,
M H Şahan ,
M Inal ,
Ö Gündüz  and
O K Arıkan
A Doğan
Affiliation:
Radiology Department, Faculty of Medicine, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey
N Bayar Muluk*
Affiliation:
Department of ENT, Faculty of Medicine, Kırıkkale University, Turkey
N Asal
Affiliation:
Department of Radiology, Faculty of Medicine, Kırıkkale University, Turkey
M H Şahan
Affiliation:
Department of Radiology, Faculty of Medicine, Kırıkkale University, Turkey
M Inal
Affiliation:
Department of Radiology, Faculty of Medicine, Kırıkkale University, Turkey
Ö Gündüz
Affiliation:
Department of Dermatology, Faculty of Medicine, Kırıkkale University, Turkey
O K Arıkan
Affiliation:
ENT Clinics, Adana Numune Training and Research Hospital, Adana, Turkey
*
Author for correspondence: Dr Nuray Bayar Muluk, Birlik Mahallesi, Zirvekent 2. Etap Sitesi, C-3 blok, No: 6-3/43, 06610 Çankaya/Ankara, Turkey E-mail: nbayarmuluk@yahoo.com Fax: +90 312 4964073
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Abstract

Objective

To investigate olfactory bulb volume and olfactory sulcus depth in patients with Behçet's disease, using magnetic resonance imaging.

Methods

Cranial magnetic resonance imaging scans of 27 adults with Behçet's disease (10 males and 17 females) and 27 healthy controls were examined. Olfactory bulb volume and olfactory sulcus depth were measured on coronal, T2-weighted, spectral pre-saturation with inversion recovery sequences.

Results

Bilateral olfactory bulb volume and right-sided olfactory sulcus depth were significantly lower in the Behçet's disease group than in the control group (p < 0.05). Left-sided olfactory sulcus depth increased with Behçet's disease duration. In both groups, olfactory bulb volume was significantly higher in the left than the right side. There were no gender differences for olfactory bulb volume and olfactory sulcus depth. Positive correlations were determined between right- and left-sided olfactory bulb volume values and between right- and left-sided olfactory sulcus depth values.

Conclusion

Behçet's disease may decrease olfactory functions, related to lower olfactory bulb volume and olfactory sulcus depth. The affected vascular system and possibly damaged neural system, nasal mucosal lesions, and prolonged nasal mucociliary clearance time may cause olfactory dysfunction. Patient follow up is recommended, with magnetic resonance imaging examinations of the olfactory system if necessary.

Keywords

Behçet DiseaseMagnetic Resonance ImagingOlfaction DisordersOlfactory BulbOlfactory Sulci
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 132 , Issue 12 , December 2018 , pp. 1088 - 1092
Copyright
Copyright © JLO (1984) Limited, 2018 

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Footnotes

Dr N Bayar Muluk takes responsibility for the integrity of the content of the paper

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