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Longitudinal course of depressive symptoms in adulthood: linear stochastic differential equation modeling

Published online by Cambridge University Press:  30 August 2012

T. Rosenström ,
M. Jokela ,
M. Hintsanen ,
L. Pulkki-Råback ,
N. Hutri-Kähönen  and
L. Keltikangas-Järvinen
T. Rosenström*
Affiliation:
IBS, Unit of Personality, Work and Health Psychology, University of Helsinki, Finland
M. Jokela
Affiliation:
IBS, Unit of Personality, Work and Health Psychology, University of Helsinki, Finland
M. Hintsanen
Affiliation:
IBS, Unit of Personality, Work and Health Psychology, University of Helsinki, Finland Helsinki Collegium for Advanced Studies, University of Helsinki, Finland
L. Pulkki-Råback
Affiliation:
IBS, Unit of Personality, Work and Health Psychology, University of Helsinki, Finland
N. Hutri-Kähönen
Affiliation:
Department of Pediatrics, Tampere University and Tampere University Hospital, Finland
L. Keltikangas-Järvinen
Affiliation:
IBS, Unit of Personality, Work and Health Psychology, University of Helsinki, Finland
*
*Address for correspondence: T. Rosenström, IBS, Unit of Personality, Work and Health Psychology, University of Helsinki (Siltavuorenpenger 1 A), PO Box 9, 00014, Helsinki, Finland. (Email: tom.rosenstrom@helsinki.fi)
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Abstract

Background

Although many studies have addressed the topic of stability versus change in depressive symptoms, few have further decomposed the change to continuous accumulation versus non-systematic state fluctuations or measurement errors. This further step requires a longitudinal follow-up and an appropriate stochastic model; it would, for example, evaluate the hypothesis that women accumulate more susceptibility events than men.

Method

A linear stochastic differential equation model was estimated for a 16-year longitudinal course of depressive symptoms in the Young Finns community sample of 3596 participants (1832 women, 1764 men). This model enabled us to decompose the variance in depression symptoms into a stable trait, cumulative effects and state/error fluctuations.

Results

Women showed higher mean levels and higher variance of depressive symptoms than men. In men, the stable trait accounted for the majority [61%, 90% confidence interval (CI) 48.9–69.2] of the total variance, followed by cumulative effects (23%, 90% CI 9.9–41.7) and state/error fluctuations (16%, 90% CI 5.6–23.2). In women, the cumulative sources were more important than among men and accounted for 44% (90% CI 23.6–58.9) of the variance, followed by stable individual differences (32%, 90% CI 18.5–54.2) and state fluctuations (24%, 90% CI 19.1–27.3).

Conclusions

The results are consistent with previous observations that women suffer more depression than men, and have more variance in depressive symptoms. We also found that continuously accumulating effects are a significant contributor to between-individual differences in depression, especially for women. Although the accumulating effects are often confounded with non-systematic state fluctuations, the latter are unlikely to exceed 27% of the total variance of depressive symptoms.

Keywords

Adult developmentcommunity samplecontinuous-time modeldepressive symptomsgender differenceslongitudinal studystochastic differential equationtime trajectoriesunipolar depression
Type
Original Articles
Information
Psychological Medicine , Volume 43 , Issue 5 , May 2013 , pp. 933 - 944
Copyright
Copyright © Cambridge University Press 2012

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