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Progesterone interaction with sperm plasma membrane, calcium influx and induction of the acrosome reaction

Published online by Cambridge University Press:  01 July 1999

Christopher Bray ,
Jackson CK Brown ,
Steve Publicover  and
Christopher LR Barratt
Christopher Bray
Affiliation:
Department of Medicine, University of Birmingham, Birmingham, UK
Jackson CK Brown
Affiliation:
Department of Biological Sciences, University of Birmingham, Birmingham, UK
Steve Publicover
Affiliation:
Department of Biological Sciences, University of Birmingham, Birmingham, UK
Christopher LR Barratt
Affiliation:
Assisted Conception Unit, Birmingham Women's Hospital, Birmingham, UK
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Abstract

In contrast to the classic action of steroid hormones through cytoplasmic/nuclear receptors, there is an accumulating body of data which strongly suggests that they have a direct effect on cells mediated through putative membrane receptors, a so-called non-genomic action. Although such non-genomic effects were discovered 50 years ago it is only in the last 15 years that the subject has become an area of intense research.

Type
Research Article
Information
Reproductive Medicine Review , Volume 7 , Issue 2 , July 1999 , pp. 81 - 93
Copyright
© 1999 Cambridge University Press

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