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Working Memory and Intelligence Are Associated with Victoria Symptom Validity Test Hard Item Performance in Patients With Intractable Epilepsy

Published online by Cambridge University Press:  21 January 2013

Therese A. Keary ,
Thomas W. Frazier ,
Catherine J. Belzile ,
Jessica S. Chapin ,
Richard I. Naugle ,
Imad M. Najm  and
Robyn M. Busch
Therese A. Keary
Affiliation:
Department of Psychiatry and Psychology, Cleveland Clinic, Cleveland, Ohio Psychology Service, Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio
Thomas W. Frazier
Affiliation:
Center for Pediatric Behavioral Health, Cleveland Clinic, Cleveland, Ohio
Catherine J. Belzile
Affiliation:
Department of Psychology, John Carroll University, University Heights, Ohio
Jessica S. Chapin
Affiliation:
Department of Psychiatry and Psychology, Cleveland Clinic, Cleveland, Ohio Epilepsy Center, Cleveland Clinic, Cleveland, Ohio
Richard I. Naugle
Affiliation:
Department of Psychiatry and Psychology, Cleveland Clinic, Cleveland, Ohio Epilepsy Center, Cleveland Clinic, Cleveland, Ohio
Imad M. Najm
Affiliation:
Epilepsy Center, Cleveland Clinic, Cleveland, Ohio
Robyn M. Busch*
Affiliation:
Department of Psychiatry and Psychology, Cleveland Clinic, Cleveland, Ohio Epilepsy Center, Cleveland Clinic, Cleveland, Ohio
*
Correspondence and reprint requests to: Robyn M. Busch, Cleveland Clinic Epilepsy Center, 9500 Euclid Avenue, P57, Cleveland, OH 44195. E-mail: buschr@ccf.org
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Abstract

Loring et al. (Journal of Clinical and Experimental Neuropsychology, 2005:27;610–617) observed relationships between VSVT hard item performance and IQ and memory indices in epilepsy surgical candidates, with a potential confound of low FSIQ on VSVT performance. The present study replicated the Loring et al. study in a larger sample and extended their findings by examining the relationships among VSVT performance, FSIQ, and working memory. A total of 404 patients with medically intractable epilepsy completed a comprehensive neuropsychological assessment. Differences in WAIS-III and WMS-III performance were examined as a function of VSVT hard score categories as determined by Grote et al. (2000)—that is, valid, >20/24; questionable, 18–20; or invalid, <18. Quantile regression models were constructed to compare the strength of the relationship between FSIQ and VSVT at various points of the FSIQ distribution. Linear regression analyses examined working memory as a potential mediator between FSIQ and VSVT performance. The invalid group performed more poorly than the valid and questionable groups on multiple measures of intelligence and memory. The strength of the relationship between FSIQ and VSVT hard item performance decreased as FSIQ increased, and working memory mediated this relationship. Results suggest VSVT hard item scores may be impacted by working memory difficulties and/or low intellectual functioning. (JINS, 2013, 19, 1–10)

Keywords

Symptom validityNeuropsychologyCognitionSeizuresIntelligenceWorking memory
Type
Research Articles
Information
Journal of the International Neuropsychological Society , Volume 19 , Issue 3 , March 2013 , pp. 314 - 323
Copyright
Copyright © The International Neuropsychological Society 2013

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Footnotes

*

Current affiliation: Department of Psychology, John Carroll University, University Heights, Ohio.

References

Baron, R.M., Kenny, D.A. (1986). The moderator-mediator variable distinction in social psychological research: Conceptual, strategic, and statistical considerations. Journal of Personality and Social Psychology, 51, 1173–1182.CrossRefGoogle ScholarPubMed
Busch, R.M., Chapin, J.S., Umashankar, G., Diehl, B., Harvey, D.J., Naugle, R.I., Najm, I.M. (2008). Poor presurgical performance on both verbal and visual memory measures is associated with low risk for memory decline following left temporal lobectomy for intractable epilepsy. Epileptic Disorders, 10(3), 199–205.Google ScholarPubMed
Busch, R.M., Naugle, R.I. (2008). Pre-surgical neuropsychological workup: Risk factors for post-surgical deficits. In H. Lüders (Ed.), Textbook of epilepsy surgery (pp. 817–825). London: Informa HealthCare.Google Scholar
Bush, S.S., Ruff, R.M., Troster, A.I., Barth, J.T., Koffler, S.P., Pliskin, N.H., Silver, C.H. (2005). Symptom validity assessment: Practice issues and medical necessity. Archives of Clinical Neuropsychology, 20, 419–426.CrossRefGoogle ScholarPubMed
Chelune, G.J., Naugle, R.I., Lüders, H., Awad, I.A. (1991). Prediction of cognitive change as a function of preoperative ability status among temporal lobectomy patients seen at 6-month follow-up. Neurology, 41(3), 399–404.CrossRefGoogle ScholarPubMed
Cohen, J. (1988). Statistical power analysis for the behavioral sciences (2nd ed.). Hillsdale, NJ: Lawrence Earlbaum Associates.Google Scholar
Cohen, J. (1992). A power primer. Psychological Bulletin, 112(1), 155–159.CrossRefGoogle ScholarPubMed
Dean, A.C., Victor, T.L., Boone, K.B., Arnold, G. (2008). The relationship of IQ to effort test performance. The Clinical Neuropsychologist, 22, 705–722.CrossRefGoogle ScholarPubMed
Doss, R.C., Chelune, G.J., Naugle, R.I. (1999). Victoria Symptom Validity Test: Compensation-seeking vs. non-compensation-seeking patients in a general medical setting. Journal of Forensic Neuropsychology, 1, 5–20.CrossRefGoogle Scholar
Enders, C.K. (2001). A primer on maximum likelihood algorithms for use with missing data. Structural Equation Modeling, 8(1), 128–141.CrossRefGoogle Scholar
Graham, J.W., Schafer, J.L. (1999). On the performance of multiple imputation for multivariate data with small sample size. In R. H. Hoyle (Ed.), Statistical strategies for small sample research (pp. 1–29). Thousand Oaks, CA: Sage Publications, Inc.Google Scholar
Green, P., Allen, L.M., Astner, K. (1996). The Word Memory Test: A user's guide to the oral and computer-administered forms, US version 1.1. Durham, NC: CogniSyst, Inc.Google Scholar
Grote, C.L., Kooker, E.K., Garron, D.C., Nyenhuis, D.L., Smith, C.A., Mattingly, M.L. (2000). Performance of compensation seeking and non-compensation seeking samples on the Victoria Symptom Validity Test: Cross-validation and extension of a standardization study. Journal of Clinical and Experimental Neuropsychology, 22(6), 709–719.CrossRefGoogle ScholarPubMed
Harvey, D.J., Naugle, R.I., Magleby, J., Chapin, J.S., Najm, I.M., Bingaman, W., Busch, R.M. (2008). Relationship between presurgical memory performance on the Wechsler Memory Scale-III and memory change following temporal resection for treatment of intractable epilepsy. Epilepsy and Behavior, 13(2), 372–375.CrossRefGoogle ScholarPubMed
Kim, S.Y., Lee, H.W., Jung, D.K., Suh, C.K., Park, S.P. (2006). Cognitive effects of low-dose topiramate compared with oxcarbazepine in epilepsy patients. Journal of Clinical Neurology, 2(2), 126–133.CrossRefGoogle ScholarPubMed
Kockelmann, E., Elger, C.E., Helmstaedter, C. (2004). Cognitive profile of topiramate as compared with lamotrigine in epilepsy patients on antiepileptic drug polytherapy: Relationships to blood serum levels and comedication. Epilepsy and Behavior, 5(5), 716–721.CrossRefGoogle ScholarPubMed
Koenker, R., Bassett, G. (1978). Regression quantiles. Econometrica, 46, 33–50.CrossRefGoogle Scholar
Koenker, R., Hallock, K.F. (2001). Quantile regression: An introduction. Journal of Economic Perspectives, 15, 143–156.CrossRefGoogle Scholar
Kraemer, H., Kiernan, M., Essex, M., Kupfer, D. (2008). How and why criteria defining moderators and mediators differ between the Baron & Kenny and MacArthur approaches. Health Psychology, 27(Suppl 2), S101–S108.CrossRefGoogle ScholarPubMed
Lee, G.P. (2010). Neuropsychology of epilepsy and epilepsy surgery. New York: Oxford University Press.Google Scholar
Loring, D.W., Lee, G.P., Meador, K.J. (2005). Victoria Symptom Validity Test performance in non-litigating epilepsy surgery candidates. Journal of Clinical and Experimental Neuropsychology, 27, 610–617.CrossRefGoogle ScholarPubMed
Loring, D.W., Marino, S., Meador, K.J. (2007). Neuropsychological and behavioral effects of anti-epilepsy drugs. Neuropsychology Review, 17, 413–425.CrossRefGoogle Scholar
Meador, K.J. (2002). Cognitive outcomes and predictive factors in epilepsy. Neurology, 58(Suppl 5), S21–S26.CrossRefGoogle ScholarPubMed
Merten, T., Bossink, L., Schmand, B. (2007). On the limits of effort testing: Symptom validity tests and severity of neurocognitive symptoms in nonlitigant patients. Journal of Clinical and Experimental Neuropsychology, 29(3), 308–318.CrossRefGoogle ScholarPubMed
Mittenberg, W., Theroux, S., Aguila-Puentes, G., Bianchini, K., Grere, K., Rayls, K. (2001). Identification of malingered head injury on the Wechsler Adult Intelligence Scale – 3rd edition. The Clinical Neuropsychologist, 15(4), 440–445.Google ScholarPubMed
Motamedi, G., Meador, K.J. (2003). Epilepsy and cognition. Epilepsy and Behavior, 4(Suppl 2), S25–S38.CrossRefGoogle ScholarPubMed
Naugle, R.I., Chelune, G.J., Cheek, R., Lüders, H., Awad, I.A. (1993). Detection of changes in material-specific memory following temporal lobectomy using the Wechsler Memory Scale-Revised. Archives of Clinical Neuropsychology, 8(5), 381–395.CrossRefGoogle ScholarPubMed
Ortinski, P., Meador, K.J. (2004). Cognitive side effects of antiepileptic drugs. Epilepsy and Behavior, 5(Suppl 1), S60–S65.CrossRefGoogle ScholarPubMed
Schafer, J.L. (2002). Multiple imputation with PAN. In L. Collins & G. Aline (Eds.), New methods for the analysis of change (pp. 357–377). Washington, DC: American Psychological Association.Google Scholar
Slick, D.J., Hopp, G., Strauss, E., Thompson, G.B. (1997). Victoria Symptom Validity Test professional manual. Odessa, FL: Psychological Assessment Resources, Inc.Google Scholar
Slick, D.J., Strauss, E., Spellacy, F.J. (1996). Victoria Symptom Validity Test: Efficiency for detecting feigned memory impairment and relationship to neuropsychological tests and MMPI-2 validity scales. Journal of Clinical and Experimental Neuropsychology, 18, 911–922.CrossRefGoogle ScholarPubMed
Slick, D.J., Tan, J.E., Strauss, E., Mateer, C.A., Harnadek, M., Sherman, E.M. (2003). Victoria Symptom Validity Test scores of patients with profound memory impairment: Nonlitigants case studies. The Clinical Neuropsychologist, 17(3), 390–394.CrossRefGoogle ScholarPubMed
Sobel, M.E. (1982). Asymptotic confidence intervals for indirect effects in structural equation models. Sociological Methodology, 13, 290–312.CrossRefGoogle Scholar
Sommer, B.R., Fenn, H.H. (2010). Review of topiramate for the treatment of epilepsy in elderly patients. Clinical Interventions in Aging, 5, 89–99.CrossRefGoogle ScholarPubMed
Tombaugh, T.N. (1996). Test of memory malingering. North Tonawanda, NY: Multi-Health Systems.Google Scholar
Wechsler, D. (1997a). Wechsler Adult Intelligence Scale-Third Edition. San Antonio, TX: The Psychological Corporation.Google Scholar
Wechsler, D. (1997b). Wechsler Memory Scale- Third Edition. Psychological Corporation.Google Scholar
Williamson, D., Drane, D., Stroup, E., Wilensky, A., Holmes, M., Miller, J. (2005). Recent seizures may distort the validity of neurocognitive test scores in patients with epilepsy. Epilepsia, 46(Suppl 8), 74.Google Scholar