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Minicircular Kinetoplast DNA of Trypanosomatidae

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Abstract

Analysis of primary structure and organization of mitochondrial (kinetoplast) DNA of flagellates occupies a prominent place in the studies of eukaryote mitochondrial genomes, owing to its unusual organization and functioning as well as to the epidemiological role of the Trypanosomatidae family. According to contemporary notions, living zooflagellates are direct descendants of the ancestral forms that gave rise to all eukaryotic kingdoms. Hence, comparative mtDNA studies of recent Trypanosomatidae open broad prospects for phylogenetic reconstructions and analysis of presumable routes of eukaryote evolution. The structure, characteristics, and functions of Trypanosomatidae minicircular kinetoplast DNA are discussed here.

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References

  1. Sather, S. and Agabian, N., Proc. Natl. Acad. Sci. USA, 1985, vol. 82, pp. 5695–5699.

    Google Scholar 

  2. Simpson, L., Intern. Rev. Cytol., 1986, vol. 99, pp. 119–179.

    Google Scholar 

  3. Simpson, L., Annu. Rev. Microbiol., 1987, vol. 41, pp. 363–382.

    Google Scholar 

  4. Laurent, M., Van Assel, S., and Steinert, M., Biochem. Biophys. Res. Communs., 1971, vol. 43, pp. 278–284.

    Google Scholar 

  5. Kleisen, C.M. and Borst, P., Biochim. Biophys. Acta, 1975, vol. 404, pp. 473–478.

    Google Scholar 

  6. Johnson, B.J., Hill, G.C., Fox, T.D., and Stuart, K., Mol. Biochem. Parasitol., 1982, vol. 5, pp. 381–390.

    Google Scholar 

  7. Heywood, P. and Weinman, D., J. Protozool., 1978, vol. 3, pp. 287–292.

    Google Scholar 

  8. Robinson, D.R. and Gull, K., Nature, 1991, vol. 352, pp. 731–733.

    Google Scholar 

  9. Perez-Morga, D.L. and Englund, P.T., Cell, 1993, vol. 74, pp. 703–711.

    Google Scholar 

  10. Chen, J., Rauch, C.A., White, J.H., et al., Cell, 1995, vol. 80, pp. 61–69.

    Google Scholar 

  11. Barrois, M., Riou, G., and Galibert, F., Proc. Natl. Acad. Sci. USA, 1981, vol. 78, pp. 3323–3327.

    Google Scholar 

  12. Tittawella, I., Carlsson, L., and Thornell, L.E., FEBS Lett., 1993, vol. 333, pp. 5–9.

    Google Scholar 

  13. Stuart, K. and Feagin, J.E., Int. Rev. Cytol., 1992, vol. 141, pp. 65–88.

    Google Scholar 

  14. Sturm, N.R. and Simpson, L., Cell, 1990, vol. 61, pp. 879–884.

    Google Scholar 

  15. Sugisaki, H. and Ray, D.S., Mol. Biochem. Parasitol., 1987, vol. 23, pp. 253–263.

    Google Scholar 

  16. Hoeijmakers, J.H. and Borst, P., Plasmid, 1982, vol. 7, pp. 210–220.

    Google Scholar 

  17. Fouts, D.L., Wolstenholme, D.R., and Boyer, H.W., J. Cell. Biol., 1978, vol. 79, pp. 329–341.

    Google Scholar 

  18. Pestov, D.G., Gladkaya, L.A., Maslov, D.A., and Kolesnikov, A.A., Mol. Biochem. Parasitol., 1990, vol. 41, pp. 135–145.

    Google Scholar 

  19. Kolesnikov, A.A., Maslov, D.A., and Podlipaev, S.A., Arch. Protistenkd., 1990, vol. 138, pp. 239–250.

    Google Scholar 

  20. Yurchenko, V.Y., Kolesnikov, A.A., and Lukes, J., Folia Parasitol., 2000, vol. 47, pp. 1–5.

    Google Scholar 

  21. Kolesnikov, A.A., Maslov, D.A., Rezepkina, L.A., and Zaitseva, G.N., Molek. Biologiya, 1984, vol. 18, pp. 591–598.

    Google Scholar 

  22. Ntambi, J.M., Marini, J.C., Bangs, J.D., et al., Mol. Biochem. Parasitol., 1984, vol. 12, pp. 273–286.

    Google Scholar 

  23. Kim, R. and Ray, D.S., Gene, 1985, vol. 40, pp. 291–299.

    Google Scholar 

  24. Maslov, D.A., Hollar, L., Haghighat, P., and Nawathean, P., Mol. Biochem. Parasitol., 1998, vol. 93, pp. 225–236.

    Google Scholar 

  25. Sa-Carvalho, D., Perez-Morga, D., and Traub-Cseko, Y.M., J. Eukaryot. Microbiol., 1993, vol. 40, pp. 317–322.

    Google Scholar 

  26. Kidane, G.Z., Hughes, D., and Simpson, L., Gene, 1984, vol. 27, pp. 265–277.

    Google Scholar 

  27. Kolesnikov, A.A., Safyanova, V.M., and Stetsenko, M.M., Med. Parazitologiya, 1984, vol. 4, pp. 37–41.

    Google Scholar 

  28. Kolesnokov, A.A. and Safyanova, V.M., Med. Parazitologiya, 1989, vol. 9, pp. 20–22.

    Google Scholar 

  29. Barker, D.C. and Arnot, D.E., Mol. Biochem. Parasitol., 1981, vol. 3, pp. 33–46.

    Google Scholar 

  30. Spithill, T.W. and Grumont, R.J., Mol. Biochem. Parasitol., 1984, vol. 12, pp. 217–236.

    Google Scholar 

  31. Spithill, T.W., Grumont, R.J., and Mitchell, G.F., J. Cell. Biochem., 1984, vol. 24, pp. 103–112.

    Google Scholar 

  32. Majumder, R. and Sen, G.P., J. Commun. Dis., 1992, vol. 24, pp. 245–246.

    Google Scholar 

  33. Smyth, A.J., Ghosh, A., Hassan, M.Q., et al., Parasitology, 1992, vol. 105, pp.183–192.

    Google Scholar 

  34. Ibrahim, M.E., Smyth, A.J., Ali, M.H., et al., Acta Trop., 1994, vol. 57, pp. 327–332.

    Google Scholar 

  35. Lee, S.Y., Lee, S.T., and Chang, K.P., J. Protozool., 1992, vol. 39, pp. 190–196.

    Google Scholar 

  36. Lee, S.T., Tarn, C., and Chang, K.P., Mol. Biochem. Parasitol., 1993, vol. 58, pp. 187–203.

    Google Scholar 

  37. Barker, D.C., Gibson, L.J., Kennedy, W.P., et al., Parasitology, 1986, vol. 92, pp. 139–174.

    Google Scholar 

  38. Eresh, S., de Bruijn, M.H., Mendosa-Leon, J.A., and Barker, D.C., Trans. R. Soc. Trop. Med. Hyg., 1995, vol. 89, pp. 231–236.

    Google Scholar 

  39. Pacheco, R.S., Martinez, J.E., Valderrama, L., et al., Mol. Biochem. Parasitol., 1995, vol. 69, pp. 197–209.

    Google Scholar 

  40. Kolesnikov, A.A., Jirku, M., Peckova, H., et al., Folia Parasitol., 1995, vol. 42, pp. 251–254.

    Google Scholar 

  41. Baron, L.I., Yurchenko, V.Yu., and Kolesnikov, A.A., Mol. Biol., 1995, vol. 29, pp. 1341–1348.

    Google Scholar 

  42. Borst, P., Fase-Fowler, F., Steinert, M., and Van Vassel, S., Exp. Cell. Res., 1977, vol. 110, pp. 167–173.

    Google Scholar 

  43. Yurchenko, V.Yu., Martinkina, L.P., Merzlyak, E.M., et al., Mol. Biol., 1998, vol. 32, pp. 998–1003.

    Google Scholar 

  44. Yurchenko, V.Yu., Hobza, R., Benada, O., and Lukes, J., Exp. Parasitol., 1999, vol. 92, pp. 215–218.

    Google Scholar 

  45. Avila, H., Goncalves, A.M., Nehme, N.S., et al., Mol. Biochem. Parasitol., 1990, vol. 42, pp. 175–187.

    Google Scholar 

  46. Recinos, R.F., Kirchhoff, L.V., and Donelson, J.E., Mol. Biochem. Parasitol., 1994, vol. 63, pp. 59–67.

    Google Scholar 

  47. Myler, P.J., Acta Trop., 1993, vol. 53, pp. 205–225.

    Google Scholar 

  48. Ponzi, M., Birago, C., and Battaglia, P.A., Mol. Biochem. Parasitol., 1984, vol. 13, pp. 111–119.

    Google Scholar 

  49. Metzenberg, S. and Agabian, N., Proc. Natl. Acad. Sci. USA, 1994, vol. 91, pp. 5962–5966.

    Google Scholar 

  50. Chen, K.K. and Donelson, J.E., Proc. Natl. Acad. Sci. USA, 1980, vol. 77, pp. 2445–2449.

    Google Scholar 

  51. Songa, E.B., Paindavoine, P., Wittouck, E., et al., Mol. Biochem. Parasitol., 1990, vol. 43, pp. 167–179.

    Google Scholar 

  52. Masiga, D.K. and Gibson, W.C., Mol. Biochem. Parasitol., 1990, vol. 40, pp. 279–283.

    Google Scholar 

  53. Riou, G., Baltz, T., Gabillot, M., and Pautrizel, R., Mol. Biochem. Parasitol., 1980, vol. 1, pp. 97–105.

    Google Scholar 

  54. Martinkina, L.P., Kolesnikov, A.A., Streltsov, S.A., et al., Mol. Biol., 1998, vol. 32, pp. 614–620.

    Google Scholar 

  55. Tzfati, Y. and Shlomai, J., Mol. Biochem. Parasitol., 1998, vol. 94, pp. 137–141.

    Google Scholar 

  56. Hassan, H.F. and Coombs, G.H., Comp. Biochem. Physiol. [B]., 1986, vol. 84, pp. 219–223.

    Google Scholar 

  57. Maslov, D.A. and Simpson, L., Mol. Cell. Biol., 1994, vol. 14, pp. 8174–8182.

    Google Scholar 

  58. Blom, D., de Haan, A., Van den Burg, J., et al., RNA, 2000, vol. 6, pp. 21–135.

    Google Scholar 

  59. Faria de Silva, P.M., Sole-Cava, A.M., Soares, M.J., et al., J. Protozool., 1991, vol. 38, pp. 489–494.

    Google Scholar 

  60. Riou, G.F., Belnat, P. and Benard, J., J. Biol. Chem., 1980, vol. 255, pp. 5141–5144.

    Google Scholar 

  61. Frasch, A.C., Hajduk, S.L., Hoeijmakers, J.H., et al., Biochim. Biophys. Acta, 1980, vol. 607, pp. 397–410.

    Google Scholar 

  62. Harris, E., Kropp, G., Belli, A., et al., J. Clin. Microbiol., 1998, vol. 36, pp. 1989–1995.

    Google Scholar 

  63. Ray, D.S., Mol. Cell. Biol., 1989, vol. 9, pp. 1357–1365.

    Google Scholar 

  64. Simpson, L., Mol. Biochem. Parasitol., 1997, vol. 86, pp. 133–141.

    Google Scholar 

  65. Marini, J.C., Effron, P.N., Goodman, T.C., et al., J. Biol. Chem., 1984, vol. 259, pp. 8974–8979.

    Google Scholar 

  66. Commers-Ampt, J., Lutgerink, J., and Borst, P., Nucleic Acids Res., 1991, vol. 19, pp. 1745–1751.

    Google Scholar 

  67. Wuyts, N., Chokesajjawatee, N., and Panyim, S., Southeast Asian J. Trop. Med. Public Health, 1994, vol. 25, pp. 266–271.

    Google Scholar 

  68. Qu, Y.C., Giroud, C., and Baltz, T., Mol. Biochem. Parasitol., 1991, vol. 46, pp. 97–102.

    Google Scholar 

  69. Gibson, W. and Garside, L., Mol. Biochem. Parasitol., 1990, vol. 42, pp. 45–53.

    Google Scholar 

  70. Solari, A., Venegas, J., Gonzalez, E., and Vasques, C., J. Protozool., 1991, vol. 38, pp. 559–565.

    Google Scholar 

  71. Wincker, P., Britto, C., Pereira, J.B., et al., Am. J. Trop. Med. Hyg., 1994, vol. 51, pp. 771–777.

    Google Scholar 

  72. Monteon, V.M., Furuzawa-Carballeda, J., Alejandre-Aguilar, R., et al., Exp. Parasitol., 1996, vol. 83, pp. 267–274.

    Google Scholar 

  73. Maslov, D.A., Sturm, N.R., Niner, B.M., et al., Mol. Cell. Biol., 1992, vol. 12, pp. 56–67.

    Google Scholar 

  74. Uezato, H., Hagiwara, K., Hosokawa, A., et al., J. Dermatol., 1998, vol. 25, pp. 623–631.

    Google Scholar 

  75. Birkenmeyer, L., Sugisaki, H., and Ray, D.S., J. Biol. Chem., 1987, vol. 262, pp. 2384–2392.

    Google Scholar 

  76. Rezepkina, L.A., Maslov, D.A., and Kolesnikov, A.A., Biokhimiya, 1984, vol. 49, pp. 444–454.

    Google Scholar 

  77. Melendy, T. and Ray, D.S., J. Biol. Chem., 1989, vol. 264, pp. 1870–1876.

    Google Scholar 

  78. Torri, A.F. and Englund, P.T., J. Biol. Chem., 1992, vol. 267, pp. 4786–4792.

    Google Scholar 

  79. Nolan, L.L., Rivera, J.H., and Khan, N.N., Biochim. Biophys. Acta, 1992, vol. 1120, pp. 322–328.

    Google Scholar 

  80. Sheline, C., Melendy, T., and Ray, D.S., Mol. Cell. Biol., 1989, vol. 9, pp. 169–176.

    Google Scholar 

  81. Ferguson, M.L., Torri, A.F., Perez-Morga, D., et al., J. Cell. Biol., 1994, vol. 126, pp. 631–639.

    Google Scholar 

  82. Ferguson, M.L., Torri, A.F., Ward, D.C., and Englund, P.T., Cell, 1992, vol. 70, pp. 621–629.

    Google Scholar 

  83. Shlomai, J. and Zadok, A., Nucleic Acids Res., 1984, vol. 12, pp. 8017–8028.

    Google Scholar 

  84. Singh, N. and Rastogi, A.K., Biochim. Biophys. Acta, 1999, vol. 1444, pp. 263–268.

    Google Scholar 

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  1. V. Yu. Yurchenko

    Present address: The Picower Institute for Medical Research, Manhasset, New York, 11030, USA

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  1. Biological Faculty, Moscow State University, Moscow, 119899, Russia

    V. Yu. Yurchenko & A. A. Kolesnikov

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Yurchenko, V.Y., Kolesnikov, A.A. Minicircular Kinetoplast DNA of Trypanosomatidae. Molecular Biology 35, 1–10 (2001). https://doi.org/10.1023/A:1004813414607

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