Skip to main content
Log in

Effect of Acute Hyperglycaemia on the Serum Fructosamine and Blood Glycated Haemoglobin Concentrations in Canine Samples

  • Published:
Veterinary Research Communications Aims and scope Submit manuscript

Abstract

The effect was studied of an acute and non-persistent hyperglycaemia on the serum fructosamine and blood glycated haemoglobin concentrations in canine samples. Five dogs were given glucose solution intravenously and blood samples were taken from each dog before and at 5, 15, 30, 60 and 120 min and 24 h after the infusion. There was an intense hyperglycaemia 5 min after the injection was given, but no statistically significant differences in the serum fructosamine and glycated haemoglobin were observed. It was concluded that an acute and transient hyperglycaemia does not cause significant changes in the glycated haemoglobin and fructosamine concentrations in healthy dogs.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

REFERENCES

  • Elliot, D.A., Nelson, R.W., Feldman, E.C. and Neal, L.A., 1997. Glycosylated hemoglobin concentrations in the blood of healthy dogs and cats with naturally developing diabetes mellitus, pancreatic β-cell neoplasia, hyperadrenocorticism and anemia. Journal of the American Veterinary Medical Association, 211, 723-727

    Google Scholar 

  • Haberer, B. and Reusch, C.E., 1998. Glycated haemoglobin in various pathological conditions: investigations based on a new, fully automated method. Journal of Small Animal Practice, 39, 510-517

    Google Scholar 

  • Jensen, A.L., 1992. Serum fructosamine in canine diabetes mellitus. An initial study. Veterinary Research Communications, 16, 1-9

    Google Scholar 

  • Jensen, A.L., 1993. Various protein and albumin corrections of the serum fructosamine concentrations in the diagnosis of canine diabetes mellitus. Veterinary Research Communications, 17, 13-23

    Google Scholar 

  • Jensen, A.L., 1995. Glycated blood proteins in canine diabetes mellitus. Veterinary Record, 137, 401-405

    Google Scholar 

  • Jensen, A.L. and Aaes, H., 1992. Reference interval and critical difference for canine serum fructosamine concentration. Veterinary Research Communications, 16, 317-325

    Google Scholar 

  • Kawamoto, M., Kaneko, J.J., Heusner, A.A., Feldman, E.C. and Koizumi, I., 1992. Relation of fructosamine to serum protein albumin and glucose concentrations in healthy and diabetic dogs. American Journal of Veterinary Research, 53, 851-855

    Google Scholar 

  • Loste, A., 1998. Estudio de la fructosamina y hemoglobina glicosilada en muestras caninas y su aportación al control de la glucemia, (PhD thesis, University of Zaragoza, Spain)

    Google Scholar 

  • Loste, A. and Marca, M.C., 1999. Study of the effect of total serum protein and albumin concentrations on canine fructosamine concentration. Canadian Journal of Veterinary Research, 63, 138-141

    Google Scholar 

  • Lutz, T.A., Rand, J.S. and Ryan, E., 1995. Fructosamine concentrations in hyperglycemic cats. Canadian Veterinary Journal, 36, 155-159

    Google Scholar 

  • Reusch, C.E. and Hoyer-Ott, M., 1994. Glycated hemoglobin and fructosamine: studies of in-vitro glycosylation. Journal of Veterinary Internal Medicine, 9, 162-165

    Google Scholar 

  • Rijnberk, A., 1996. Protocols for function tests. In: Clinical Endocrinology of Dogs and Cats (Kluwer Academic, Dordrecht)

    Google Scholar 

  • Smith, J.E., Wood, P.A. and Moore, K., 1982. Evaluation of a colorimetric method for canine glycosylated hemoglobin. American Journal of Veterinary Research, 43, 700-701

    Google Scholar 

  • Thorensen, S.I. and Bredal, W.P., 1996. Clinical usefulness of fructosamine measurements in diagnosing and monitoring feline diabetes mellitus. Journal of Small Animal Practice, 37, 64-68

    Google Scholar 

  • Wood, P.A. and Smith, J.E., 1982. Elevation rate of glycosylated hemoglobins in dogs after induction of experimental diabetes mellitus. Metabolism, 31, 906-909

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Marca, M., Loste, A. & Ramos, J. Effect of Acute Hyperglycaemia on the Serum Fructosamine and Blood Glycated Haemoglobin Concentrations in Canine Samples. Vet Res Commun 24, 11–16 (2000). https://doi.org/10.1023/A:1006317103422

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1006317103422

Navigation