Abstract
Effects of drying on the measurement of mechanical properties of bone by nanoindentation methods have been examined. Tests were conducted to measure the elastic modulus and hardness of two cross-sectional cortical specimens obtained from adjacent areas of bovine femur. One specimen was thoroughly dried in air prior to testing while the other was stored in deionized water. The properties of osteons and interstitial lamellae showed statistically significant differences (plt; 0.0001) and were therefore investigated separately. Drying was found to increase the elastic modulus by 9.7% for interstitial lamellae and 15.4% for osteons. The hardness was also found to increase by 12.2% for interstitial lamellae and 17.6% for osteons.
Similar content being viewed by others
References
J. Y. Rho, T. Y. Tsui and G. M. Pharr, Biomaterials 18 (1997) 1325.
G. M. Pharr and W. C. Oliver, MRS Bulletin 17 (1992) 28.
W. C. Oliver and G. M. Pharr, J. Mater. Res. 7 (1992) 1564.
M. F. Doerner and W. D. Nix, J. Mater. Res. 1 (1986) 601.
D. S. Harding, W. C. Oliver and G. M. Pharr, MRS Symp. Proc. 356 (1995) 663.
G. M. Pharr, D. S. Harding and W. C. Oliver, in “Mechanical Properties and Deformation Behaviour of Materials Having Ultra-fine Microstructures”, edited by Nastasi, Parkin and Gleiter (Kluwer Academic Publishers, Netherlands, 1993) p. 449.
F. G. Evans and M. Lebow, J. Appl. Physiol. 3 (1951) 563.
F. G. Evans, in “Mechanical Properties of Bone”, (Charles C. Thomas, Springfield, IL, 1973) p. 43.
H. Yamada, in “Strength of Biological Materials”, (Williams & Wilkins, Baltimore, MD, 1970) p. 74.
P. R. Townsend and R. M. Rose, J. Biomech. 8 (1975) 199.
J. D. Currey, J. Biomech. 21 (1988) 439.
M. W. Jameson, J. A. A. Hood and B. G. Tidmarsh, J. Biomech. 26 (1993) 1055.
G. P. Evans, J. C. Behiri, J. D. Currey and W. Bonfield, J. Mater. Sci. Mater. Med. 1 (1990) 38.
W. T. Dempster and R. T. Liddicoat, Amer. J. Anat. 91 (1952) 331.
R. Amprino, Acta Anat. 34 (1958) 161.
J. M. Ten Cate, B. Nyvad, Y. M. Van De Plas Schesimons and O. Fejerskov, J. Dent. Res. 70 (1991) 1371.
J. B. Finlay and W. R. Hardie, Proc. Inst. Mech. Eng. 208 (1994) 27.
J. K. Weaver, J. Bone Joint Surg. 48-A (1966) 273.
J.-M. Dorlot, G. L'esperance and A. Meunier, Trans. 32nd Orthop. Res. Soc. 11 (1986) 330.
D. D. Lee and M. J. Glimcher, J. Molec. Biol. 217 (1991) 487.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Rho, JY., Pharr, G.M. Effects of drying on the mechanical properties of bovine femur measured by nanoindentation. Journal of Materials Science: Materials in Medicine 10, 485–488 (1999). https://doi.org/10.1023/A:1008901109705
Issue Date:
DOI: https://doi.org/10.1023/A:1008901109705