Skip to main content
Original Articles

The WHO Quality of Life Assessment Instrument (WHOQOL-100)

Published Online:https://doi.org/10.1027/1015-5759.22.3.207

This study scrutinizes the ability of the WHO quality of life assessment instrument (WHOQOL-100) to discriminate (1) between psychiatric outpatients and the general population, and (2) between subgroups of psychiatric outpatients. A sample of Dutch adult psychiatric outpatients (N = 410) completed the WHOQOL-100. In addition, DSM-IV Axis-I and Axis-II diagnoses were obtained. Compared with the general population, psychiatric outpatients scored significantly lower on all aspects of self-reported quality of life (QOL). Within the group of outpatients, participants with DSM-IV diagnoses had lower scores than those without. Participants with diagnoses on both Axis-I and Axis-II of DSM-IV (comorbidity) had the lowest self-reported QOL. It is concluded that in psychiatric outpatients, outcome scores of self-reported QOL were negatively related to presence and degree of psychopathology. The WHOQOL-100 has good discriminant ability for psychiatric outpatients.

References

  • Andrews, G. Peters, L. Guzman, A-M. Bird, K. (1995). A comparison of the two structured diagnostic interviews: CIDI and SCAN. Australian and New Zealand Journal of Psychiatry, 29, 124– 132 First citation in articleCrossrefGoogle Scholar

  • Angermeyer, M.C. Holzinger, A. Matschinger, H. Stengler-Wenzke, K. (2002). Depression and quality of life: Results of a follow-up study. International Journal of Social Psychiatry, 48, 189– 199 First citation in articleCrossrefGoogle Scholar

  • Bobes, J. González, M.P. (1997). Quality of life in schizophrenia. In H. Katschnig, H. Freeman, & N. Sartorius (Eds.), Quality of life in mental disorders (pp. 165-178). Chichester: Wiley First citation in articleGoogle Scholar

  • Bonicatto, S.C. Dew, M.A. Zaratiegui, R. Lorenzo, L. Pecina, P. (2001). Adult outpatients with depression: Worse quality of life than in other chronic medical diseases in Argentina. Social Science and Medicine, 52, 911– 919 First citation in articleCrossrefGoogle Scholar

  • Cohen, J. (1988). Statistical power analysis for the behavioral sciences . Hillsdale, NJ: Erlbaum First citation in articleGoogle Scholar

  • Covinsky, K.E. Wu, A.W. Landefeld, S. Connors, A.F. Phillips, R.S. Tsevat, J. Dawson, N.V. Lynn, J. Fortinsky, R.H. (1999). Health status versus quality of life in older patients: Does the distinction matter?. American Journal of Medicine, 106, 435– 440 First citation in articleCrossrefGoogle Scholar

  • De Vries, J. (1996). Beyond health status. Construction and validation of the Dutch WHO Quality of Life assessment instrument . Ph.D. Thesis. Tilburg: Tilburg University First citation in articleGoogle Scholar

  • De Vries, J. Van Heck, G.L. (1995). The Dutch version of the WHOQOL-100 (In Dutch: De Nederlandse versie van de WHOQOL-100) . Tilburg: Tilburg University First citation in articleGoogle Scholar

  • De Vries, J. Van Heck, G.L. (1997). The World Health Organization Quality of Life Assessment Instrument (WHOQOL-100): Validation study with the Dutch version. European Journal of Psychological Assessment, 13, 164– 178 First citation in articleLinkGoogle Scholar

  • De Vries, J. Van Heck, G.L. (2003). De Nederlandse handleiding van de WHOQOL . [The Dutch WHOQOL manual]. Tilburg University: Tilburg First citation in articleGoogle Scholar

  • De Vries, J. Seebregts, A. Drent, M. (2000). Assessing health status and quality of life in idiopathic pulmonary fibrosis: Which measure should be used?. Respiratory Medicine, 94, 273– 278 First citation in articleCrossrefGoogle Scholar

  • De Vries, J. Michielsen, H.J. Van Heck, G.L. Drent, M. (2004). Measuring fatigue in sarcoidosis: The Fatigue Assessment Scale (FAS). British Journal of Health Psychology, 9, 279– 291 First citation in articleCrossrefGoogle Scholar

  • Devinsky, O. Cramer, J.A. (1993). Introduction: Quality of life in epilepsy. Epilepsia, 34(suppl 4), S1– 3 First citation in articleGoogle Scholar

  • First, M.B. Spitzer, R.L. Gibbon, M. Williams, J.B.W. (1997). The Structured Clinical Interview for DSM-IV Axis-II Disorders . Washington, DC: American Psychiatric Press First citation in articleGoogle Scholar

  • Giel, R. Nienhuis, F.J. (1996). SCAN-2.1: Schedules for clinical assessment in neuropsychiatry. (In Dutch: Vragenschema's voor klinische beoordeling in neuropsychiatrie) . Geneva: WHO, Division of Mental Health/Groningen: University of Groningen, Division of Social Psychiatry First citation in articleGoogle Scholar

  • Gladis, M.M. Gosch, E.A. Dishuk, N.M. Crits-Cristoph, P. (1999). Quality of life: Expanding the scope of clinical significance. Journal of Consulting and Clinical Psychology, 67, 320– 331 First citation in articleCrossrefGoogle Scholar

  • Katschnig, H. Krautgartner, M. (2002). Quality of Life: A new dimension in mental health care. In N. Sartorius, W. Gaebel, J.J. Lopez-Ibor, & M. Maj (Eds.), Psychiatry in society (pp. 171-191). Chichester: Wiley First citation in articleGoogle Scholar

  • Larsen, R.J. Buss, D.M. (2005). Personality psychology. Domains of knowledge about human nature (2nd ed. pp. 420-423). New York: McGraw-Hill First citation in articleGoogle Scholar

  • Maffei, C. Fossati, A. Agostoni, I. Barraco, A. Bagnato, M. Deborah, D. Namia, C. Novella, L. Petrachi, M. (1997). Interrater reliability and internal consistency of the Structured Clinical Interview for DSM-IV Axis II Personality Disorders (SCID-II), version 2. Journal of Personality Disorders, 11, 279– 284 First citation in articleCrossrefGoogle Scholar

  • Masthoff, E.D. Trompenaars, F.J. Van Heck, G.L. Hodiamont, P.P.G. De Vries, J. (2005). Validation of the WHOQOL-100 in a population of Dutch adult psychiatric outpatients. European Journal of Psychiatry, 20, 465– 473 First citation in articleCrossrefGoogle Scholar

  • Nelson, C.B. Rehm, J. Üstün, T.B. Grant, B. Chatterji, S. (1999). Factor structures for DSM-IV substance disorder criteria endorsed by alcohol, cannabis, cocaine, and opiate users: Results from the WHO reliability and validity study. Addiction, 94, 843– 855 First citation in articleCrossrefGoogle Scholar

  • O'Carroll, R.E. Smith, K. Couston, M. Cossar, J.A. Hayes, P.C. (2000). A comparison of the WHOQOL-100 and the WHOQOL-Brief in detecting change in quality of life following liver transplantation. Quality of Life Research, 9, 121– 124 First citation in articleCrossrefGoogle Scholar

  • Örsel, S. Akdemir, A. Daġ, I. (2004). The sensitivity of quality-of-life scale WHOQOL-100 to psychopathological measures in schizophrenia. Comprehensive Psychiatry, 45, 57– 61 First citation in articleCrossrefGoogle Scholar

  • Power, M. Harper, A. Bullinger, M. The WHOQOL Group (1999). The World Health Organization WHOQOL-100: Tests of the universality of quality of life in 15 different cultural groups worldwide. Health Psychology, 18, 495– 505 First citation in articleCrossrefGoogle Scholar

  • Rijnders, C.A.Th. Van den Berg, J.F.M. Hodiamont, P.P.G. Nienhuis, F.J. Furer, J.W. Mulder, J. Giel, R. (2000). Psychometric properties of the Schedules for Clinical Assessment in Neuropsychiatry (SCAN-2.). Social Psychiatry and Psychiatric Epidemiology, 35, 348– 352 First citation in articleCrossrefGoogle Scholar

  • Schneier, F.R. (1997). Quality of life in anxiety disorders. In H. Katschnig, H. Freeman, & N. Sartorius (Eds.), Quality of life in mental disorders (pp. 149-163). Chichester: Wiley First citation in articleGoogle Scholar

  • Simon, E.S. (2003). Social and economic burden of mood disorders. Biological Psychiatry, 54, 208– 215 First citation in articleCrossrefGoogle Scholar

  • Skevington, S.M. (1999). Measuring quality of life in Britain: Introducing the WHOQOL-100. Journal of Psychosomatic Research, 47, 449– 459 First citation in articleCrossrefGoogle Scholar

  • Skevington, S.M. Wright, A. (2001). Changes in the quality of life of patients receiving antidepressant medication in primary care: Validation of the WHOQOL-100. British Journal of Psychiatry, 178, 261– 267 First citation in articleCrossrefGoogle Scholar

  • Skevington, S.M. Carse, M.S. Williams, A.C. (2001). Validation of the WHOQO-100: Pain management improves quality of life for chronic pain patients. Clinical Journal of Pain, 17, 264– 275 First citation in articleCrossrefGoogle Scholar

  • Smith, K.W. Avis, N.E. Assmann, S.F. (1999). Distinguishing between quality of life and health status in quality of life research: A meta-analysis. Quality of Life Research, 8, 447– 459 First citation in articleCrossrefGoogle Scholar

  • Spitzer, R.L. Williams, J.B.W. Gibbon, M. First, M.B. (1990). Structured Clinical Interview for DSM-III-R Personality Disorders (SCID-II) . Washington, DC: American Psychiatric Press First citation in articleGoogle Scholar

  • Suurmeijer, T.P.B.M. Reuvekamp, M.F. Aldenkamp, B.P. (2001). Social functioning, psychological functioning, and quality of life in epilepsy. Epilepsia, 42, 1160– 1168 First citation in articleCrossrefGoogle Scholar

  • Weertman, A. Arntz, A. Kerkhofs, M.L.M. (2000). The Structured Clinical Interview for DSM-IV Axis-II Disorders (In Dutch: Gestructureerd klinisch interview voor DSM-IV As-II persoonlijkheidsstoornissen) . Lisse: Swets & Zeitlinger First citation in articleGoogle Scholar

  • WHOQOL Group (1994). The development of the World Health Organization Quality of Life Assessment instrument (the WHOQOL). In J. Orley & W. Kuyken (Eds.), Quality of life assessment: International perspectives (pp. 41-60). Berlin: Springer-Verlag First citation in articleGoogle Scholar

  • WHOQOL Group (1998). The World Health Organization Quality of Life Assessment (WHOQOL): Development and general psychometric properties. Social Science and Medicine, 46, 1569– 1585 First citation in articleCrossrefGoogle Scholar

  • Wing, J.K. Babor, T. Brugha, T. Burke, J. Cooper, J.E. Giel, R. Jablenski, A. Regier, D. Sartorius, N. (1990). Schedules for clinical assessment in neuropsychiatry. Archives of General Psychiatry, 47, 589– 593 First citation in articleCrossrefGoogle Scholar

  • Wing, J.K. Sartorius, N. Üstün, T.B. (1998). Diagnosis and clinical measurement in psychiatry a reference manual for SCAN . Cambridge: Cambridge University Press First citation in articleGoogle Scholar