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Nucleotide sequence and secondary structure of potato spindle tuber viroid

Abstract

The viroid of the potato spindle tuber disease (PSTV) is a covalently closed ring of 359 ribonucleotides. As a result of intramolecular base pairing, a serial arrangement of double-helical sections and internal loops form a unique rod-like secondary structure. PSTV is the first pathogen of a eukaryotic organism for which the complete molecular structure has been established.

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Gross, H., Domdey, H., Lossow, C. et al. Nucleotide sequence and secondary structure of potato spindle tuber viroid. Nature 273, 203–208 (1978). https://doi.org/10.1038/273203a0

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