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Regulation of transcription by proteins that control the cell cycle

Nature volume 389, pages 149–152 (1997)Cite this article

Abstract

In eukaryotes, progression of a cell through the cell cycle is partly controlled at the level of transcriptional regulation. Yeast and mammalian cells use similar mechanisms to achieve this regulation. Although gaps still remain, progress has been made recently in connecting the links between the cell's cycle and its transcriptional machinery.

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Figure 1: Connections between cell-cycle regulators and the mammalian transcription machinery.

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Acknowledgements

I thank E. Harlow, R. Erikson and I Sanchez for suggestions on this review.

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  1. the Department of Molecular and Cellular Biology, Harvard University, 16 Divinity Avenue, Cambridge, 02138, Massachusetts, USA

    Brian D. Dynlacht

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Dynlacht, B. Regulation of transcription by proteins that control the cell cycle. Nature 389, 149–152 (1997). https://doi.org/10.1038/38225

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