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Blood-vessel formation

Bridges that guide and unite

Nature volume 465, pages 697–699 (2010)Cite this article

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To form new blood vessels, the endothelial tip cells of two existing vessels come together by the process of anastomosis. But how do they find each other? Macrophages seem to provide a bridge and mediate their union.

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Figure 1: Bridging branch formation.

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Authors and Affiliations

  1. Thomas Schmidt and Peter Carmeliet are at the Vesalius Research Center, Katholieke Universiteit Leuven, and the Flanders Institute for Biotechnology, Leuven, B-3000, Belgium. peter.carmeliet@vib-kuleuven.be ,

    Thomas Schmidt & Peter Carmeliet

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  1. Thomas Schmidt
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  2. Peter Carmeliet
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Schmidt, T., Carmeliet, P. Bridges that guide and unite. Nature 465, 697–699 (2010). https://doi.org/10.1038/465697a

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