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Cell biology

Dormant and restless skin stem cells

Nature volume 489, pages 215–217 (2012)Cite this article

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It has been unclear whether a uniform group of stem cells gives rise to most cells in the epidermis. A study reveals the presence of at least two stem-cell populations that have different proliferative abilities. See Article p.257

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Figure 1: Models for self-renewal of the epidermis.

References

  1. Mascré, G. et al. Nature 489, 257–262 (2012).

    Article  ADS  Google Scholar 

  2. Potten, C. S. Cell Tissue Kinet. 7, 77–88 (1974).

    CAS  PubMed  Google Scholar 

  3. Clayton, E. et al. Nature 446, 185–189 (2007).

    Article  CAS  ADS  Google Scholar 

  4. Doupé, D. P . et al. Dev. Cell 18, 317–323 (2010).

    Article  Google Scholar 

  5. Wilson, A. et al. Cell 135, 1118–1129 (2008).

    Article  CAS  Google Scholar 

  6. Barker, N. et al. Nature 449, 1003–1007 (2007).

    Article  CAS  ADS  Google Scholar 

  7. Jaks, V. et al. Nature Genet. 40, 1291–1299 (2008).

    Article  CAS  Google Scholar 

  8. Barrandon, Y. & Green, H. Proc. Natl Acad. Sci. USA 84, 2302–2306 (1987).

    Article  CAS  ADS  Google Scholar 

  9. Pellegrini, G. et al. J. Cell Biol. 145, 769–782 (1999).

    Article  CAS  Google Scholar 

  10. Rama, P. et al. N. Engl. J. Med. 363, 147–155 (2010).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Laura De Rosa and Michele De Luca are at the Center for Regenerative Medicine 'Stefano Ferrari', University of Modena and Reggio Emilia, Modena 41125, Italy.,

    Laura De Rosa & Michele De Luca

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  1. Laura De Rosa
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  2. Michele De Luca
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Correspondence to Michele De Luca.

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De Rosa, L., De Luca, M. Dormant and restless skin stem cells. Nature 489, 215–217 (2012). https://doi.org/10.1038/489215a

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