Abstract
A prospective study was carried out to compare the efficacy of electroretinography, fundus fluorescein angiography and clinical examination in identifying those at risk of rubeotic glaucoma following central retinal vein occlusion (CRVO). Our preliminary observations are described. The findings suggest a complementary role for electroretinography in the management of CRVO. Particularly significant were interocular differences in 30Hz flicker latency, the ability to elicit pattern ERGs and the ratio of scotopic and photopic a:b wave amplitudes. Of the clinical measures the depth of the relative afferent pupil defect was a sensitive indicator of rubeosis. Factors of lesser statistical prognostic value included poor visual acuity and the extent of deep retinal haemorrhages. Fundus fluorescein angiography in this study had limited value in predicting those patients at risk of rubeosis.
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Magargal LE, Brown GC, Augsburger JJ, Parrish RK : Neovascular glaucoma following central retinal vein obstruction. Ophthalmology 1981; 88: 1095–100.
Hayreh SS : Classification of Central Retinal Vein Occlusion. Ophthalmology 1983; 90: 458–72.
Laatikainen L and Kohner EM : Fluorescein angiography and its prognostic significance in retinal vein occlusion. Br J Ophthalmol 1976; 60: 411–18.
May DR, Klein ML, Peyman GA, Rauchand M : Xenon arc panretinal photocoagulation for central retinal vein occlusion: a randomised prospective study. Br J Ophthalmol 1979; 63: 725–34.
Laatkainen L : Preliminary report on effect of retinal panphotocoagulation on rubeosis iridis and neovascular glaucoma. Br J Ophthalmol 1977; 61: 278–84.
Katz A : Clinical and experimental studies on retinal neovascularisation. Am J Ophthalmol 1982; 94: 715–43.
Magargal LE, Brown GC, Augsburger JJ, Donoso LA : Efficacy of panretinal photocoagulation in preventing neovascular glaucoma following ischaemic central retinal vein occlusion. Ophthalmology 1982; 89: 780–4.
Welch JC and Augsburger JJ : Assessment of angiographic retinal capillary non-perfusion in central retinal vein occlusion. Am J Ophthalmol 1987; 106: 353–6.
Sabates R, Hirose T, McMeel JW : Electroretinography in the prognosis and classification of central retinal vein occlusion. Arch Ophthalmol, 1983; 101: 232–5.
Barber C, Galloway N, Reacher M, Salem H : The role of the electroretinogram in the management of central retinal vein occlusion. Doc Ophthalmol Proc Series 1984; 40: 149–59.
Johnson MA, Marcus S, Elman MJ, McPhee TJ : Neovascularisation in central retinal vein occlusion: electroretinographic findings. Arch Ophthalmol 1988; 106: 348–52.
Kaye SB and Harding SP : Early electroretinography in unilateral central retinal vein occlusion as a predictor of rubeosis iridis. Arch Ophthalmol 1988; 106: 353–6.
Breton ME, Quinn GE, Keene S, Dahmen JC, Brucker AJ : Electroretinogram parameters at presentation as predictors of rubeosis in central retinal vein occlusion patients. Ophthalmology 1989; 96: 1343–52.
Lawill T : The bar pattern electroretinogram. Doc Ophthalmol 1984; 40: 1–10.
Holder GE : Significance of abnormal pattern electroretinography in anterior visual pathway dysfunction. Br J Ophthalmol 1987; 71: 166–71.
Magargal EL, Donoso LA, Sanborn GE : Retinal ischaemia and risk of neovascularisation following central retinal vein occlusion. Ophthalmology 1982; 89: 1241–5.
Thompson DA, Corbett JJ, Cox TA : How to measure the relative afferent pupil defect. Surv Ophthalmol 1981: 26: 39–42.
Thompson DA and Drasdo N : An improved method for using the DTL fibre in electroretinography. Ophthal, Physiol Opt 1987; 7: 315–19.
Servais GE, Thompson HS, Hayreh SS : Relative afferent pupil defect in central retinal vein occlusion Ophthalmology 1986; 93: 301–3.
Minturn J and Brown GC : Progression of nonischaemic central retinal vein obstruction to the ischaemic type. Ophthalmology 1986; 93: 1158–62.
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Morrell, A., Thompson, D., Gibson, J. et al. Electroretinography as a prognostic indicator or neovascularisationin CRVO. Eye 5, 362–368 (1991). https://doi.org/10.1038/eye.1991.58
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DOI: https://doi.org/10.1038/eye.1991.58
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