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Diabetic peripheral neuropathy and prevalence of erectile dysfunction in Japanese patients aged <65 years with type 2 diabetes mellitus: The Dogo Study

International Journal of Impotence Research volume 29, pages 30–34 (2017)Cite this article

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Abstract

Only limited epidemiological evidence exists regarding the relationship between diabetic neuropathy and erectile dysfunction (ED) among Japanese patients with type 2 diabetes mellitus. To investigate the relationship between diabetic neuropathy and ED among Japanese patients with type 2 diabetes mellitus, a multicenter cross-sectional study was conducted in 287 male Japanese patients with type 2 diabetes mellitus, age (19–65 years). Diabetic neuropathy was diagnosed if the patients showed two or more of the following three characteristics: neuropathic symptoms, decreased or disappeared Achilles tendon reflex and/or abnormal vibration perception. ED, moderate to severe ED, and severe ED were defined as present when a subject had a Sexual Health Inventory for Men score <22, <12 and <8, respectively. The prevalence values of diabetic neuropathy and severe ED were 47.0 and 39.0%, respectively. Diabetic neuropathy was independently positively associated with severe ED, but not ED and moderate ED: the adjusted odds ratio was 1.90 (95% confidence interval: 1.08–3.38). No relationships were found between diabetic retinopathy or diabetic nephropathy and ED. Diabetic neuropathy is positively associated with severe erectile dysfunction among Japanese type 2 diabetes mellitus patients aged <65 years.

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Acknowledgements

This study was supported by JSPS KAKENHI Grants (217090583 and 23790697). We thank Eriko Kawamoto from Matsuyama City Hospital, Keiko Kikuchi from Ehime University and Eri Furukawa from Furukawa Clinic. JSPS KAKENHI Grants (217090583 and 23790697).

Author information

Authors and Affiliations

  1. Department of Epidemiology and Preventive Medicine, Ehime University Graduate School of Medicine,

    S Furukawa, H Senba & Y Miyake

  2. Shitsukawa, Toon, Japan

    S Furukawa, H Senba & Y Miyake

  3. Epidemiology and Medical Statistics Unit, Translational Research Center, Ehime University Hospital,

    S Furukawa & Y Miyake

  4. Shitsukawa, Toon, Japan

    S Furukawa & Y Miyake

  5. Department of Internal Medicine, Yawatahama General City Hospital, Yawatahama, Japan

    T Sakai

  6. Department of Internal Medicine, Matsuyama Shimin Hospital,

    T Niiya & Y Todo

  7. Otemachi, Matsuyama, Japan

    T Niiya & Y Todo

  8. Department of Internal Medicine, Saiseikai Matsuyama Hospital, Matsuyama, Japan

    H Miyaoka

  9. Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine,

    T Miyake, H Senba & Y Hiasa

  10. Shitsukawa, Toon, Japan

    T Miyake, H Senba & Y Hiasa

  11. Department of Lifestyle-related Medicine and Endocrinology, Ehime University Graduate School of Medicine,

    S Yamamoto & B Matsuura

  12. Shitsukawa, Toon, Japan

    S Yamamoto & B Matsuura

  13. Department of Public Health, Juntendo University School of Medicine,

    K Maruyama & T Tanigawa

  14. Bunkyo, Tokyo, Japan

    K Maruyama & T Tanigawa

  15. Department of Internal Medicine, Ehime Prefectural Central Hospital, Matsuyama, Japan

    T Ueda

  16. Department of Internal Medicine, Saiseikai Saijo Hospital, Saijo, Japan

    M Torisu

  17. Department of Internal Medicine, Ehime Niihama Hospital, Niihama, Japan

    H Minami

  18. Department of Internal Medicine, Saiseikai Imabari Hospital, Imabari, Japan

    M Onji

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  1. S Furukawa
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  2. T Sakai
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  3. T Niiya
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  4. H Miyaoka
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  5. T Miyake
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  6. S Yamamoto
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  7. K Maruyama
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  8. T Ueda
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  9. H Senba
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  10. Y Todo
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  11. M Torisu
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  12. H Minami
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  13. M Onji
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  14. T Tanigawa
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  15. B Matsuura
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  16. Y Hiasa
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  17. Y Miyake
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Corresponding author

Correspondence to S Furukawa.

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Furukawa, S., Sakai, T., Niiya, T. et al. Diabetic peripheral neuropathy and prevalence of erectile dysfunction in Japanese patients aged <65 years with type 2 diabetes mellitus: The Dogo Study. Int J Impot Res 29, 30–34 (2017). https://doi.org/10.1038/ijir.2016.40

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  • DOI: https://doi.org/10.1038/ijir.2016.40

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