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Bariatric surgery for treatment of obesity

Abstract

This article focuses on recent trends and outcomes of bariatric surgery. The outcomes discussed include perioperative morbidity and mortality, weight loss, long-term complications and the impact of bariatric surgery on comorbidities, cardiovascular risk and mortality.

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References

  1. Catenacci VA, Hill JO, Wyatt HR . The obesity epidemic. Clin Chest Med 2009; 30: 415–444, vii.

    Article  PubMed  Google Scholar 

  2. Fisher BL, Schauer P . Medical and surgical options in the treatment of severe obesity. Am J Surg 2002; 184: 9S–16S.

    Article  PubMed  Google Scholar 

  3. Flegal KM, Carroll MD, Ogden CL, Curtin LR . Prevalence and trends in obesity among US adults, 1999–2008. JAMA 2010; 303: 235–241.

    Article  CAS  PubMed  Google Scholar 

  4. Picot J, Jones J, Colquitt JL, Gospodarevskaya E, Loveman E, Baxter L et al. The clinical effectiveness and cost-effectiveness of bariatric (weight loss) surgery for obesity: a systematic review and economic evaluation. Health Technol Assess 2009; 13: 1–190, 215–357, iii–iv.

    Article  CAS  PubMed  Google Scholar 

  5. Buchwald H, Oien DM . Metabolic/bariatric surgery worldwide 2008. Obes Surg 2009; 19: 1605–1611.

    Article  PubMed  Google Scholar 

  6. Buchwald H, Avidor Y, Braunwald E, Jensen MD, Pories W, Fahrbach K et al. Bariatric surgery: a systematic review and meta-analysis. JAMA 2004; 292: 1724–1737.

    Article  CAS  PubMed  Google Scholar 

  7. Maggard MA, Shugarman LR, Suttorp M, Maglione M, Sugerman HJ, Livingston EH et al. Meta-analysis: surgical treatment of obesity. Ann Intern Med 2005; 142: 547–559.

    Article  PubMed  Google Scholar 

  8. Schauer PR, Burguera B, Ikramuddin S, Cottam D, Gourash W, Hamad G et al. Effect of laparoscopic Roux-en-Y gastric bypass on type 2 diabetes mellitus. Ann Surg 2003; 238: 467–484; discussion 84–85.

    PubMed  PubMed Central  Google Scholar 

  9. Brethauer SA, Hammel JP, Schauer PR . Systematic review of sleeve gastrectomy as staging and primary bariatric procedure. Surg Obes Relat Dis 2009; 5: 469–475.

    Article  PubMed  Google Scholar 

  10. Agaba EA, Shamseddeen H, Gentles CV, Sasthakonar V, Gellman L, Gadaleta D . Laparoscopic vs open gastric bypass in the management of morbid obesity: a 7-year retrospective study of 1,364 patients from a single center. Obes Surg 2008; 18: 1359–1363.

    Article  PubMed  Google Scholar 

  11. Sekhar N, Torquati A, Youssef Y, Wright JK, Richards WO . A comparison of 399 open and 568 laparoscopic gastric bypasses performed during a 4-year period. Surg Endosc 2007; 21: 665–668.

    Article  CAS  PubMed  Google Scholar 

  12. Carelli AM, Youn HA, Kurian MS, Ren CJ, Fielding GA . Safety of the laparoscopic adjustable gastric band: 7-year data from a U.S. center of excellence. Surg Endosc 2010; 24: 1819–1823.

    Article  PubMed  Google Scholar 

  13. DeMaria EJ, Sugerman HJ, Kellum JM, Meador JG, Wolfe LG . Results of 281 consecutive total laparoscopic Roux-en-Y gastric bypasses to treat morbid obesity. Ann Surg 2002; 235: 640–645; discussion 5–7.

    Article  PubMed  PubMed Central  Google Scholar 

  14. Maher JW, Martin Hawver L, Pucci A, Wolfe LG, Meador JG, Kellum JM . Four hundred fifty consecutive laparoscopic Roux-en-Y gastric bypasses with no mortality and declining leak rates and lengths of stay in a bariatric training program. J Am Coll Surg 2008; 206: 940–944; discussion 4–5.

    Article  PubMed  Google Scholar 

  15. Menenakos E, Stamou KM, Albanopoulos K, Papailiou J, Theodorou D, Leandros E . Laparoscopic sleeve gastrectomy performed with intent to treat morbid obesity: a prospective single-center study of 261 patients with a median follow-up of 1 year. Obes Surg 2010; 20: 276–282.

    Article  PubMed  Google Scholar 

  16. Buchwald H, Estok R, Fahrbach K, Banel D, Sledge I . Trends in mortality in bariatric surgery: a systematic review and meta-analysis. Surgery 2007; 142: 621–632; discussion 32–35.

    Article  PubMed  Google Scholar 

  17. Flum DR, Belle SH, King WC, Wahed AS, Berk P, Chapman W et al. Perioperative safety in the longitudinal assessment of bariatric surgery. N Engl J Med 2009; 361: 445–454.

    Article  PubMed  Google Scholar 

  18. Morino M, Toppino M, Forestieri P, Angrisani L, Allaix ME, Scopinaro N . Mortality after bariatric surgery: analysis of 13,871 morbidly obese patients from a national registry. Ann Surg 2007; 246: 1002–1007; discussion 7–9.

    Article  PubMed  Google Scholar 

  19. Poulose BK, Griffin MR, Zhu Y, Smalley W, Richards WO, Wright JK et al. National analysis of adverse patient safety for events in bariatric surgery. Am Surg 2005; 71: 406–413.

    PubMed  Google Scholar 

  20. Cotter SA, Cantrell W, Fisher B, Shopnick R . Efficacy of venous thromboembolism prophylaxis in morbidly obese patients undergoing gastric bypass surgery. Obes Surg 2005; 15: 1316–1320.

    Article  PubMed  Google Scholar 

  21. Podnos YD, Jimenez JC, Wilson SE, Stevens CM, Nguyen NT . Complications after laparoscopic gastric bypass: a review of 3464 cases. Arch Surg 2003; 138: 957–961.

    Article  PubMed  Google Scholar 

  22. Tice JA, Karliner L, Walsh J, Petersen AJ, Feldman MD . Gastric banding or bypass? A systematic review comparing the two most popular bariatric procedures. Am J Med 2008; 121: 885–893.

    Article  PubMed  Google Scholar 

  23. Mehran A, Szomstein S, Zundel N, Rosenthal R . Management of acute bleeding after laparoscopic Roux-en-Y gastric bypass. Obes Surg 2003; 13: 842–847.

    Article  PubMed  Google Scholar 

  24. Nguyen NT, Longoria M, Chalifoux S, Wilson SE . Gastrointestinal hemorrhage after laparoscopic gastric bypass. Obes Surg 2004; 14: 1308–1312.

    Article  PubMed  Google Scholar 

  25. Nguyen NT, Rivers R, Wolfe BM . Early gastrointestinal hemorrhage after laparoscopic gastric bypass. Obes Surg 2003; 13: 62–65.

    Article  PubMed  Google Scholar 

  26. Carrodeguas L, Szomstein S, Zundel N, Lo Menzo E, Rosenthal R . Gastrojejunal anastomotic strictures following laparoscopic Roux-en-Y gastric bypass surgery: analysis of 1291 patients. Surg Obes Relat Dis 2006; 2: 92–97.

    Article  PubMed  Google Scholar 

  27. Gumbs AA, Duffy AJ, Bell RL . Incidence and management of marginal ulceration after laparoscopic Roux-Y gastric bypass. Surg Obes Relat Dis 2006; 2: 460–463.

    Article  PubMed  Google Scholar 

  28. Naef M, Mouton WG, Naef U, Kummer O, Muggli B, Wagner HE . Graft survival and complications after laparoscopic gastric banding for morbid obesity—lessons learned from a 12-year experience. Obes Surg 2010; 20: 1206–1214.

    Article  PubMed  Google Scholar 

  29. Bauman RW, Pirrello JR . Internal hernia at Petersen's space after laparoscopic Roux-en-Y gastric bypass: 6.2% incidence without closure—a single surgeon series of 1047 cases. Surg Obes Relat Dis 2009; 5: 565–570.

    Article  PubMed  Google Scholar 

  30. Iannelli A, Buratti MS, Novellas S, Dahman M, Amor IB, Sejor E et al. Internal hernia as a complication of laparoscopic Roux-en-Y gastric bypass. Obes Surg 2007; 17: 1283–1286.

    Article  PubMed  Google Scholar 

  31. Ahmed AR, Rickards G, Johnson J, Boss T, O’Malley W . Radiological findings in symptomatic internal hernias after laparoscopic gastric bypass. Obes Surg 2009; 19: 1530–1535.

    Article  PubMed  Google Scholar 

  32. Toh SY, Zarshenas N, Jorgensen J . Prevalence of nutrient deficiencies in bariatric patients. Nutrition 2009; 25: 1150–1156.

    Article  CAS  PubMed  Google Scholar 

  33. Garb J, Welch G, Zagarins S, Kuhn J, Romanelli J . Bariatric surgery for the treatment of morbid obesity: a meta-analysis of weight loss outcomes for laparoscopic adjustable gastric banding and laparoscopic gastric bypass. Obes Surg 2009; 19: 1447–1455.

    Article  PubMed  Google Scholar 

  34. Himpens J, Dobbeleir J, Peeters G . Long-term results of laparoscopic sleeve gastrectomy for obesity. Ann Surg 2010; 252: 319–324.

    Article  PubMed  Google Scholar 

  35. Melton GB, Steele KE, Schweitzer MA, Lidor AO, Magnuson TH . Suboptimal weight loss after gastric bypass surgery: correlation of demographics, comorbidities, and insurance status with outcomes. J Gastrointest Surg 2008; 12: 250–255.

    Article  PubMed  Google Scholar 

  36. Patel S, Szomstein S, Rosenthal RJ . Reasons and outcomes of reoperative bariatric surgery for failed and complicated procedures (excluding adjustable gastric banding). Obes Surg 2010; e-pub ahead of print 30 July 2010; doi:10.1007/s11695-010-0234-8.

    Article  Google Scholar 

  37. Spyropoulos C, Kehagias I, Panagiotopoulos S, Mead N, Kalfarentzos F . Revisional bariatric surgery: 13-year experience from a tertiary institution. Arch Surg 2010; 145: 173–177.

    Article  PubMed  Google Scholar 

  38. Brolin RE, Cody RP . Weight loss outcome of revisional bariatric operations varies according to the primary procedure. Ann Surg 2008; 248: 227–232.

    Article  PubMed  Google Scholar 

  39. Nesset EM, Kendrick ML, Houghton SG, Mai JL, Thompson GB, Que FG et al. A two-decade spectrum of revisional bariatric surgery at a tertiary referral center. Surg Obes Relat Dis 2007; 3: 25–30; discussion.

    Article  PubMed  Google Scholar 

  40. Buchwald H, Estok R, Fahrbach K, Banel D, Jensen MD, Pories WJ et al. Weight and type 2 diabetes after bariatric surgery: systematic review and meta-analysis. Am J Med 2009; 122: 248–256, e5.

    Article  PubMed  Google Scholar 

  41. DiGiorgi M, Rosen DJ, Choi JJ, Milone L, Schrope B, Olivero-Rivera L et al. Re-emergence of diabetes after gastric bypass in patients with mid- to long-term follow-up. Surg Obes Relat Dis 2010; 6: 249–253.

    Article  PubMed  Google Scholar 

  42. Sugerman HJ, Wolfe LG, Sica DA, Clore JN . Diabetes and hypertension in severe obesity and effects of gastric bypass-induced weight loss. Ann Surg 2003; 237: 751–776; discussion 7–8.

    PubMed  PubMed Central  Google Scholar 

  43. Schauer PR, Ikramuddin S, Gourash W, Ramanathan R, Luketich J . Outcomes after laparoscopic Roux-en-Y gastric bypass for morbid obesity. Ann Surg 2000; 232: 515–529.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  44. Sjostrom L, Narbro K, Sjostrom CD, Karason K, Larsson B, Wedel H et al. Effects of bariatric surgery on mortality in Swedish obese subjects. N Engl J Med 2007; 357: 741–752.

    Article  PubMed  Google Scholar 

  45. Adams TD, Gress RE, Smith SC, Halverson RC, Simper SC, Rosamond WD et al. Long-term mortality after gastric bypass surgery. N Engl J Med 2007; 357: 753–761.

    Article  CAS  PubMed  Google Scholar 

  46. Flum DR, Koepsell T . The clinical and economic correlates of misdiagnosed appendicitis: nationwide analysis. Arch Surg 2002; 137: 799–804; discussion.

    Article  PubMed  Google Scholar 

  47. DeMaria EJ, Pate V, Warthen M, Winegar DA . Baseline data from American Society for Metabolic and Bariatric Surgery-designated Bariatric Surgery Centers of Excellence using the Bariatric Outcomes Longitudinal Database. Surg Obes Relat Dis 2010; 6: 347–355.

    Article  PubMed  Google Scholar 

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Correspondence to P R Schauer.

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Competing interests

SA Brethauer received consulting fees from Ethicon Endosurgery and lecture fees from Covidien. PR Schauer has received Educational grants from Stryker Endoscopy, Gore, Baxter, Covidien, Allergen and Research grants from Ethicon Endosurgery, Bard-Davol. PR Schauer is on the Scientific Advisory Board for Ethicon Endosurgery, Stryker Endoscopy, Bard-Davol, Barosense, Surgiquest, Cardinal/Snowden Pincer, and is on the Board of Directors for Remedy MD and Surgical Excellence LLC. PR Schauer has also served as a consultant for Ethicon Endosurgery, Bard-Davol and Gore. The remaining authors declare no conflict of interest.

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Eldar, S., Heneghan, H., Brethauer, S. et al. Bariatric surgery for treatment of obesity. Int J Obes 35 (Suppl 3), S16–S21 (2011). https://doi.org/10.1038/ijo.2011.142

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