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Severe and long-lasting hypotension occuring immediately after parathyroidectomy in hypertensive hemodialysis patients: a case series

Journal of Human Hypertension volume 27, pages 399–401 (2013)Cite this article

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Secondary hyperparathyroidism of hemodialysis patients is associated with hypertension. Parathyroidectomy might cause a mild and gradual decrease in blood pressure. We describe a case series of severe and long-lasting hypotension starting immediately after parathyroidectomy, possibly related to resetting of intracellular calcium levels and attenuation of the vascular response to calcium.

Primary, secondary and tertiary forms of hyperparathyroidism are associated with hypertension.1 Severe secondary hyperparathyroidism is an indication for corrective parathyroidectomy. Some studies have reported that parathyroidectomy induces a mild and gradual drop in blood pressure (5–10 mm Hg). Other studies showed no effect at all.2, 3, 4 A recent work utilizing 24-h ambulatory blood pressure monitoring concluded that blood pressure increases after parathyroidectomy.5 However, a substantial hypotensive effect has not yet been reported.

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Authors and Affiliations

  1. Institute of Nephrology and Hypertension, Chaim Sheba Medical Center, Tel Hashomer, Israel

    A Leiba, M S Cohen, D Dinour & E J Holtzman

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  1. A Leiba
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  2. M S Cohen
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  3. D Dinour
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  4. E J Holtzman
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Correspondence to A Leiba.

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Leiba, A., Cohen, M., Dinour, D. et al. Severe and long-lasting hypotension occuring immediately after parathyroidectomy in hypertensive hemodialysis patients: a case series. J Hum Hypertens 27, 399–401 (2013). https://doi.org/10.1038/jhh.2012.49

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