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Association of cord blood platelet count and volume with hemoglobin in healthy term infants

Journal of Perinatology volume 31, pages 258–262 (2011)Cite this article

Subjects

Abstract

Objective:

The aim of this study was to investigate relationships of cord blood cells in healthy term infants both from vaginal and Cesarean sections.

Study Design:

The study sample comprised 167 consecutive cord blood collections accepted for processing in an accredited cord blood bank. The effect of varying anticoagulant-to-blood ratio was excluded by standardizing the cell concentrations to reflect the values in native blood. Statistical analysis included descriptive statistics, simple linear regression analysis, Mann–Whitney U-test, cumulative frequency plots and Smirnov two-sample test.

Result:

As expected, hemoglobin correlated with red blood cell concentration. Interestingly, mean platelet volume was associated with hemoglobin, red blood cell concentration and hematocrit. The platelet count was inversely associated with the parameters.

Conclusion:

The observed associations of cord blood hemoglobin with mean platelet volume and platelet count reflect the physiology of fetal hematopoiesis at term.

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Acknowledgements

We thank all the participants of the CB bank program and the staff of the Finnish Cord Blood Bank. This work was funded by the Finnish Red Cross Blood Service Research Fund and the Nona and Kullervo Väre Foundation.

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Authors and Affiliations

  1. The Finnish Red Cross Blood Service, Helsinki, Finland

    M Eskola, S Juutistenaho, K Aranko & R Kekomäki

  2. Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Helsinki, Finland

    S Sainio

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  1. M Eskola
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  2. S Juutistenaho
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  3. K Aranko
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  4. S Sainio
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  5. R Kekomäki
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Correspondence to M Eskola.

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The authors declare no conflict of interest.

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Eskola, M., Juutistenaho, S., Aranko, K. et al. Association of cord blood platelet count and volume with hemoglobin in healthy term infants. J Perinatol 31, 258–262 (2011). https://doi.org/10.1038/jp.2010.95

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  • DOI: https://doi.org/10.1038/jp.2010.95

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