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Variability of resistive indices in the anterior cerebral artery during fontanel compression in preterm and term neonates measured by transcranial duplex sonography

Journal of Perinatology volume 34, pages 306–310 (2014)Cite this article

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Abstract

Objective:

To determine the normal range of resistive index (RI) variability in clinically/neurologically unremarkable preterm and term infants and to compare the hemodynamic response to transient elevation of intracranial pressure.

Study Design:

We measured RIs at baseline and following brief fontanel compression, assessing for differences in mean baseline and compression values and percent change.

Result:

One hundred and twenty-nine subjects were included in the study. Mean baseline RI and normal range were 0.7 in preterm (0.54 to 0.86) and 0.66 in term infants (0.52 to 0.8; P=0.001). Mean RI during compression was 0.71 in preterm and 0.68 in term infants (P=0.015). Mean percent change between baseline and compression was 5.86% in preterm and 7.45% in term infants (P=0.092).

Conclusion:

No difference in the hemodynamic response to transient elevation of intracranial pressure between different gestational groups, suggesting no significant differences in autoregulatory response.

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Authors and Affiliations

  1. Division of Pediatric Radiology, Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Charlotte R. Bloomberg Children’s Center, Sheikh Zayed Tower, Baltimore, MD, USA

    C Zamora, A Tekes, E Alqahtani, O T Kalayci & T A G M Huisman

  2. Division of Neonatology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA

    F Northington

  3. Department of Pediatrics, Neurological Intensive Care Nursery, Johns Hopkins University School of Medicine, Baltimore, MD, USA

    F Northington & T A G M Huisman

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  1. C Zamora
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  4. O T Kalayci
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Correspondence to T A G M Huisman.

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Zamora, C., Tekes, A., Alqahtani, E. et al. Variability of resistive indices in the anterior cerebral artery during fontanel compression in preterm and term neonates measured by transcranial duplex sonography. J Perinatol 34, 306–310 (2014). https://doi.org/10.1038/jp.2014.11

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  • DOI: https://doi.org/10.1038/jp.2014.11

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