Two new studies describe germline mutations in BAP1 in putatively dissimilar cancer-related syndromes. The spectrum of neoplasms associated with these germline mutations suggest that BAP1 has an important tumor suppressor function in multiple tissues.
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Goldstein, A. Germline BAP1 mutations and tumor susceptibility. Nat Genet 43, 925–926 (2011). https://doi.org/10.1038/ng.956
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DOI: https://doi.org/10.1038/ng.956
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