The National Center for Biotechnology Information has created the dbGaP public repository for individual-level phenotype, exposure, genotype and sequence data and the associations between them. dbGaP assigns stable, unique identifiers to studies and subsets of information from those studies, including documents, individual phenotypic variables, tables of trait data, sets of genotype data, computed phenotype-genotype associations, and groups of study subjects who have given similar consents for use of their data.
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References
The GAIN Collaborative Research Group. Nat. Genet. 39, 1045–1051 (2007).
Lowrance, W.W. & Collins, F.S. ETHICS: identifiability in genomic research. Science 317, 600–602 (2007).
Harold, E.R. XML Bible 2nd edn. (Hungry Minds, Indianapolis, Indiana, USA, 2001).
Bray, T., Paoli, J., Sperberg-McQueen, C.M., Maler, E. & Yergeau, F. Extensible Markup Language (XML) 1.0 4th edn. (World Wide Web Consortium (W3C), 2006) <http://www.w3.org/TR/REC-xml/>.
Clayton, D.G. et al. Nat. Genet. 37, 1243–1246 (2005).
Devlin, B. & Roeder, K. Biometrics 55, 997–1004 (1999).
Acknowledgements
Thanks to T. Manolio, J. Coleman, F Collins and C. O'Donnell for useful comments and discussion. This research was supported by the Intramural Research Program of the US National Institutes of Health, National Library of Medicine.
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Mailman, M., Feolo, M., Jin, Y. et al. The NCBI dbGaP database of genotypes and phenotypes. Nat Genet 39, 1181–1186 (2007). https://doi.org/10.1038/ng1007-1181
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DOI: https://doi.org/10.1038/ng1007-1181
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