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Unravelling the stealth effect

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Poly(ethylene glycol) helps nanomaterials evade the immune system by modifying the composition of proteins that are adsorbed on the surface of the materials.

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Figure 1: Schematic representation of the effect of PEGylation on the binding of plasma proteins to the surface of polystyrene nanoparticles.

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Correspondence to Rodney F. Minchin.

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Butcher, N., Mortimer, G. & Minchin, R. Unravelling the stealth effect. Nature Nanotech 11, 310–311 (2016). https://doi.org/10.1038/nnano.2016.6

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