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  • Year in Review
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Antithrombotic therapy in 2014

Making headway in anticoagulant and antiplatelet therapy

Despite favourable results in pivotal clinical trials involving novel direct oral anticoagulants, vitamin K antagonists remain the most commonly prescribed anticoagulant. Newer oral anticoagulants are slated for a wide range of additional indications, and specific antidotes to neutralize associated bleeding complications are currently under development.

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Figure 1: The new-generation non-vitamin K anticoagulants that inhibit thrombin and factor Xa.

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Correspondence to Jawed Fareed.

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Fareed, J. Making headway in anticoagulant and antiplatelet therapy. Nat Rev Cardiol 12, 70–71 (2015). https://doi.org/10.1038/nrcardio.2014.222

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