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Osteoarthritis in 2010

New takes on treatment and prevention

Nature Reviews Rheumatology volume 7, pages 75–76 (2011)Cite this article

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How can we optimize the management of osteoarthritis? Recent studies into the efficacy and mechanisms of interventions that target nociceptive mechanisms, lower-extremity musculature and ligament integrity reflect the progress being made in this field.

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References

  1. Guccione, A. A. et al. The effect of specific medical conditions on the functional limitations of elders in the Framingham Study. Am. J. Public Health 4, 351–358 (1994).

    Article  Google Scholar 

  2. Lane, N. E. et al. Tanezumab for treatment of pain from osteoarthritis of the knee. N. Engl. J. Med. 363, 1521–1531 (2010).

    Article  CAS  Google Scholar 

  3. Felson, D. T. The verdict favors nonsteroidal antiinflammatory drugs for treatment of osteoarthritis and a plea for more evidence on other treatments. Arthritis Rheum. 44, 1477–1480 (2001).

    Article  CAS  Google Scholar 

  4. Lo, G. H., LaValley, M., McAlindon, T. & Felson, D. T. Intra-articular hyaluronic acid in treatment of knee osteoarthritis: a meta-analysis. JAMA 290, 3115–3121 (2003).

    Article  CAS  Google Scholar 

  5. Bennell, K. L. et al. Hip strengthening reduces symptoms but not knee load in people with medial knee osteoarthritis and varus malalignment: a randomised controlled trial. Osteoarthritis Cartilage 18, 621–628 (2010).

    Article  CAS  Google Scholar 

  6. Hinman, R. S. et al. Hip muscle weakness in individuals with medial knee osteoarthritis. Arthritis Care Res. 62, 1190–1193 (2010).

    Article  Google Scholar 

  7. Lohmander, L. S., Englund, P. M., Dahl, L. L. & Roos, E. M. The long-term consequence of anterior cruciate ligament and meniscus injuries: osteoarthritis. Am. J. Sports Med. 35, 1756–1769 (2007).

    Article  Google Scholar 

  8. Frobell, R. B. et al. A randomized trial of treatment for acute anterior cruciate ligament tears. N. Engl. J. Med. 363, 331–342 (2010).

    Article  CAS  Google Scholar 

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  1. Boston University School of Medicine, Clinical Epidemiology Unit, Suite 200, 650 Albany Street, Boston, 02118, MA, USA

    David T. Felson

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  1. David T. Felson
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The author declares no competing financial interests.

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Felson, D. New takes on treatment and prevention. Nat Rev Rheumatol 7, 75–76 (2011). https://doi.org/10.1038/nrrheum.2010.228

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