Stressful life events can change the clinical expression of rheumatoid arthritis (RA). Stress increases the proinflammatory load in healthy individuals and patients with RA. A new study demonstrates that short-term experimental stress transiently increases serum IL-1β and IL-2 levels in patients with RA, but how does stress affect chronic inflammation?
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Straub, R. Stress in RA: a trigger of proinflammatory pathways?. Nat Rev Rheumatol 10, 516–518 (2014). https://doi.org/10.1038/nrrheum.2014.110
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DOI: https://doi.org/10.1038/nrrheum.2014.110
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