A recent retrospective study reporting increased risk of cardiovascular events and death with testosterone therapy has received extensive media attention. However, the authors' conclusions are highly questionable given the extensive data manipulation and serious methodological errors. Indeed, a rich body of literature strongly suggests that testosterone therapy offers cardiovascular benefits.
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A.M. has acted as a consultant for AbbVie, Auxilium, and Merck & Co, has received honoraria from Auxilium, Bayer AG, and Merck & Co, and has received research support from Antares Pharma, Auxilium, and Eli Lilly and Company. R.K. declares no competing interests.
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Morgentaler, A., Kacker, R. Testosterone and cardiovascular risk—deciphering the statistics. Nat Rev Urol 11, 131–132 (2014). https://doi.org/10.1038/nrurol.2014.24
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DOI: https://doi.org/10.1038/nrurol.2014.24
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