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Needle beats pill in gestational diabetes mellitus

Given the steady increase in the use of oral antidiabetic medication, better knowledge of their effects on neonatal outcomes in gestational diabetes mellitus is essential. Recently, Marie-Victoire Sénat and colleagues investigated the use of glyburide over standard insulin treatment in a noninferiority multicentre randomized trial, which found higher risk of perinatal complications under glyburide therapy.

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Fig. 1: Lifelong impact and interactions of biological and environmental factors in the development and outcome of GDM or T2DM.

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Correspondence to Alexandra Kautzky-Willer.

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Kautzky-Willer, A., Harreiter, J. Needle beats pill in gestational diabetes mellitus. Nat Rev Endocrinol 14, 448–449 (2018). https://doi.org/10.1038/s41574-018-0050-0

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