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SNAP-II Predicts Severe Intraventricular Hemorrhage and Chronic Lung Disease in the Neonatal Intensive Care Unit

Journal of Perinatology volume 22, pages 26–30 (2002)Cite this article

Abstract

OBJECTIVE: To determine whether the Score for Neonatal Acute Physiology, Version II (SNAP-II), improved prediction of severe (≥grade III) intraventricular hemorrhage (IVH) and chronic lung disease (CLD) when compared to models using gestational age (GA) and traditional risk factors (e.g., Apgar score, small-for-gestational-age, sex, outborn status).

STUDY DESIGN: We examined 4226 infants ≤32 weeks' GA admitted to 17 Canadian neonatal intensive care units between 1996 and 1997. We compared prediction models for severe IVH and CLD, with and without SNAP-II.

RESULTS: SNAP-II was a significant and independent predictor of severe IVH and CLD. Addition of SNAP-II to models using GA and traditional risk variables significantly (p<0.05) improved model prediction (AUC 0.8 for severe IVH; 0.83 for CLD). Models were well calibrated (p>0.05 for Hosmer-Lemeshow goodness of fit test).

CONCLUSION: Addition of SNAP-II to models using GA and traditional risk factors significantly improves prediction of severe IVH and CLD.

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Acknowledgements

The authors thank Douglas Richardson, MD, MBA, for his valuable advice in drafting the manuscript.

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Authors and Affiliations

  1. Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada

    Li-Yin Chien MPH, ScD, Paul Thiessen MD, FRCPC & Shoo K Lee MBBS, FRCPC, PhD

  2. Centre for Community Health and Health Evaluation Research, Vancouver, BC, Canada

    Li-Yin Chien MPH, ScD & Shoo K Lee MBBS, FRCPC, PhD

  3. Department of Pediatrics, Dalhousie University, Halifax, NS, Canada

    Robin Whyte MBBS, FRCPC, MSc

  4. Department of Pediatrics, University of Ottawa, Ottawa, ON, Canada

    Robin Walker MBBS, FRCPC

  5. Department of Pediatrics, Royal Columbian Hospital, New Westminster, BC, Canada

    David Brabyn MBChB, FRACP, FRCPC

Authors
  1. Li-Yin Chien MPH, ScD
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  2. Robin Whyte MBBS, FRCPC, MSc
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  3. Paul Thiessen MD, FRCPC
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  4. Robin Walker MBBS, FRCPC
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  5. David Brabyn MBChB, FRACP, FRCPC
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  6. Shoo K Lee MBBS, FRCPC, PhD
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The Canadian Neonatal Network

Additional information

This study was supported by grants 40503 and 00152 from the Medical Research Council of Canada. Additional funding was provided by the B.C. Children's Hospital Foundation; Calgary Regional Health Authority; Division of Neonatology, Children's Hospital of Eastern Ontario; Child Health Program, Health Care of St. John's; The Neonatology Program, Hospital for Sick Children; Lawson Research Institute; Midland Walwyn Capital; Division of Neonatology, McMaster Health Sciences Centre; Mount Sinai Hospital; North York General Hospital Foundation; Saint Joseph's Health Centre; University of Western Ontario; Women's College Hospital.

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Chien, LY., Whyte, R., Thiessen, P. et al. SNAP-II Predicts Severe Intraventricular Hemorrhage and Chronic Lung Disease in the Neonatal Intensive Care Unit. J Perinatol 22, 26–30 (2002). https://doi.org/10.1038/sj.jp.7210585

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